Length of mechanical restraint following haloperidol injections versus oral atypical antipsychotics for the initial treatment of acute schizophrenia: A propensity-matched analysis from the Japanese diagnosis procedure combination database

• Published in: Psychiatry research Vol. 209; no. 3; pp. 412 - 416
• Main Authors: Nakamura, Mitsuhiro, Yasunaga, Hideo, Haraguchi, Tadashi, Ando, Shuntaro, Sugihara, Toru, Horiguchi, Hiromasa, Ohe, Kazuhiko, Matsuda, Shinya, Fushimi, Kiyohide
• Format: Journal Article
• Language: English
• Published: Kidlington Elsevier Ireland Ltd 30.10.2013; Elsevier
• Subjects: Adult; Adult and adolescent clinical studies; Age Factors; Aged; Antipsychotic Agents - therapeutic use; Atypical antipsychotics; Biological and medical sciences; Case-Control Studies; Databases, Bibliographic - statistics & numerical data; Female; Haloperidol; Haloperidol - therapeutic use; Humans; Involuntary admission; Japan - epidemiology; Kaplan-Meier Estimate; Male; Medical sciences; Middle Aged; Neuropharmacology; Pharmacology. Drug treatments; Propensity score matching; Psychiatric Status Rating Scales; Psychiatry; Psycholeptics: tranquillizer, neuroleptic; Psychology. Psychoanalysis. Psychiatry; Psychopathology. Psychiatry; Psychopharmacology; Psychoses; Retrospective Studies; Schizophrenia; Schizophrenia - diagnosis; Schizophrenia - drug therapy; Schizophrenia - epidemiology; Survival analysis; Treatment Outcome; Young Adult; Japan; Schizophrenia; Propensity score matching; Survival analysis; Atypical antipsychotics; Involuntary admission; Haloperidol; Atypical antipsychotic; Neuroleptic; Psychotropic; Dopamine antagonist; Acute; Oral administration; Forced hospitalization; Butyrophenone derivatives; Japanese; Psychosis; D2 Dopamine receptor; Treatment; Length; Database; Restraint; Diagnosis; Comparative study

Abstract Differences in effectiveness between haloperidol injection and oral atypical antipsychotics in the acute-phase treatment of schizophrenia are not well examined. We retrospectively investigated whether these treatment options affected the length of mechanical restraint. We used the Japanese...