Design and statistical optimization of an effervescent floating drug delivery system of theophylline using response surface methodology - Srikanth Meka, Venkata; Ee Li, Chew; Sheshala, Ravi (Acta Pharmaceutica, 2016)
Keywords: Calorimetry, Differential Scanning - methods; Cellulose - analogs & derivatives; Cellulose - chemistry; central composite; Chemistry, Pharmaceutical - methods; Drug Carriers - chemistry; Drug Delivery Systems - methods; Drug Liberation; Excipients - chemistry; floating; gastroretentive; PEO N12K; Polyethylene Glycols - chemistry; Polymers - chemistry; Polymethacrylic Acids - chemistry; Polysaccharides, Bacterial - chemistry; Sodium Bicarbonate - chemistry; Solubility; Spectroscopy, Fourier Transform Infrared - methods; Tablets - chemistry; theophylline; Theophylline - chemistry