Stress biomarkers as predictors of transition to psychosis in at-risk mental states: Roles for cortisol, prolactin and albumin

• Published in: Journal of psychiatric research Vol. 60; pp. 163 - 169
• Main Authors: Labad, Javier, Stojanovic-Pérez, Alexander, Montalvo, Itziar, Solé, Montse, Cabezas, Ángel, Ortega, Laura, Moreno, Irene, Vilella, Elisabet, Martorell, Lourdes, Reynolds, Rebecca M., Gutiérrez-Zotes, Alfonso
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 01.01.2015
• Subjects: Adult; Albumin; At risk mental states; Biomarkers - blood; Biomarkers - metabolism; C-Reactive Protein - metabolism; Case-Control Studies; Cortisol; Female; Humans; Hydrocortisone - blood; Hydrocortisone - metabolism; Hypothalamic–pituitary–adrenal axis; Hypothalamo-Hypophyseal System - metabolism; Male; Pituitary-Adrenal System - metabolism; Prolactin; Prolactin - blood; Prolactin - metabolism; Psychiatry; Psychosis; Psychotic Disorders - blood; Psychotic Disorders - metabolism; Psychotic Disorders - psychology; Risk Factors; Saliva - metabolism; Serum Albumin - metabolism; Stress; Young Adult; Psychosis; Hypothalamic–pituitary–adrenal axis; Prolactin; Albumin; Cortisol; At risk mental states; Stress

Stress and inflammation are thought to play a role in the risk of developing a psychotic disorder. We aimed to identify stress-related biomarkers for psychosis transition in help-seeking individuals with an at-risk mental state (ARMS). We studied 39 ARMS subjects who were attending an Early Interven...