Endothelial Function, Carotid–Femoral Stiffness, and Plasma Matrix Metalloproteinase-2 in Men With Bicuspid Aortic Valve and Dilated Aorta - Tzemos, Nikolaos; Lyseggen, Erik; Silversides, Candice; Jamorski, Michal; Tong, Jeffrey H.; Harvey, Paula; Floras, John; Siu, Samuel (Journal of the American College of Cardiology, 2010)
Keywords: Adult; Aorta - pathology; Aorta - physiopathology; aortic dilation; Aortic Valve - abnormalities; Aortic Valve - diagnostic imaging; Aortic Valve - physiopathology; bicuspid valve; Biological and medical sciences; Blood Flow Velocity - physiology; Brachial Artery - diagnostic imaging; Brachial Artery - physiology; Cardiology; Cardiology. Vascular system; Cardiovascular; Cardiovascular disease; Carotid Arteries - physiology; Case-Control Studies; Congenital heart diseases. Malformations of the aorta, pulmonary vessels and vena cava; Coronary vessels; Cross-Sectional Studies; Dilatation, Pathologic; Endocardial and cardiac valvular diseases; Endothelium, Vascular - physiopathology; Femoral Artery - physiology; flow-mediated vasodilation; Heart; Heart rate; Humans; Hyperemia - physiopathology; Hypertension; Internal Medicine; Male; Matrix Metalloproteinase 2 - blood; Matrix Metalloproteinase 9 - blood; Medical sciences; MMP-2; Nitroglycerin; Plasma; Pulsatile Flow - physiology; pulse wave velocity; Sinuses; Systole - physiology; Tissue Inhibitor of Metalloproteinase-1 - blood; Tissue Inhibitor of Metalloproteinase-2 - blood; Ultrasonography; Vasodilator Agents; GTN; NO; eNOS; aortic dilation; cf-PWV; CMR; flow-mediated vasodilation; LV; pulse wave velocity; MMP; MMP-2; BAV; RT3DE; FMD; bicuspid valve; TIMP; real-time 3-dimensional imaging; tissue inhibitor of matrix metalloproteinase; carotid–femoral pulse wave velocity; glyceryl nitrate; endothelial nitric oxide synthase; left ventricle/ventricular; nitric oxide; bicuspid aortic valve; matrix metalloproteinase; cardiac magnetic resonance; Human; Biological fluid; Femur; Enzyme; Metalloendopeptidases; Cardiovascular disease; Male; Endothelial function; Congenital disease; Gelatinase A; Blood plasma; Peptidases; Cardiac valvular disease; Carotid; Bicuspid aortic valve; Hydrolases; Aorta; Stiffness; Circulatory system; Cardiology