Complement Activation Contributes to Severe Acute Respiratory Syndrome Coronavirus Pathogenesis - Gralinski, Lisa E.; Sheahan, Timothy P.; Morrison, Thomas E.; Menachery, Vineet D.; Jensen, Kara; Leist, Sarah R.; Whitmore, Alan; Heise, Mark T.; Baric, Ralph S. (mBio, 2018)
Keywords: animal models; Animals; Chemokines - blood; complement; Complement Activation; Complement C3 - deficiency; Complement C3 - genetics; coronavirus; Cytokines - blood; Disease Models, Animal; Female; Host-Microbe Biology; Host-Pathogen Interactions - immunology; Immunity, Innate; Lung - immunology; Lung - pathology; Lung - virology; Mice; Mice, Inbred C57BL; respiratory viruses; SARS Virus - immunology; SARS Virus - pathogenicity; SARS-CoV; Severe Acute Respiratory Syndrome - immunology; Severe Acute Respiratory Syndrome - virology; Viral Load; Virus Replication; coronavirus; animal models; complement; respiratory viruses; SARS-CoV