Review of an Inactivated Vaccine against Hantaviruses

• Published in: Intervirology Vol. 45; no. 4-6; pp. 328 - 333
• Main Authors: Cho, Hae-Wol, Howard, Colin R., Lee, Ho-Wang
• Format: Journal Article
• Language: English
• Published: Basel, Switzerland S. Karger AG 2002
• Subjects: Adult; Aged; Antibodies, Viral - blood; Enzyme-Linked Immunosorbent Assay; Female; Hantavirus; Hantavirus - immunology; Humans; Male; Middle Aged; Vaccination; Vaccines, Inactivated - immunology; Viral Vaccines - adverse effects; Viral Vaccines - immunology; Haemorrhagic fever with renal syndrome; Neutralizing antibody; Hantavirus

Objective: Hantaviruses cause haemorrhagic fever with renal syndrome and result in severe morbidity and mortality in humans. Safe and effective vaccines are needed to reduce the incidence of human illness. In this study, the immune response to an inactivated hantavirus vaccine was measured in 64 hum...