Long-term benefit of DAAs on gut dysbiosis and microbial translocation in HCV-infected patients with and without HIV coinfection

• Published in: Scientific reports Vol. 13; no. 1; pp. 14413 - 13
• Main Authors: Chuaypen, Natthaya, Jinato, Thananya, Avihingsanon, Anchalee, Nookaew, Intawat, Tanaka, Yasuhito, Tangkijvanich, Pisit
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 02.09.2023; Nature Publishing Group; Nature Portfolio
• Subjects: 631/337; 692/4017; Acetic acid; Antiviral agents; Antiviral drugs; Digestive system; Dysbacteriosis; Enzyme-linked immunosorbent assay; Fatty acid-binding protein; Fatty acids; Fibrosis; Gastrointestinal tract; Gene expression; Hepatitis C; HIV; Human immunodeficiency virus; Humanities and Social Sciences; Intestinal microflora; Lipopolysaccharides; Longitudinal studies; Microbiota; multidisciplinary; rRNA 16S; Science; Science (multidisciplinary); Translocation

Long-term effect of Direct-acting antivirals (DAAs) on gut microbiota, short-chain fatty acids (SCFAs) and microbial translocation in patients with hepatitis C virus (HCV) infection who achieve sustained virological response (SVR) were limited. A longitudinal study of 50 patients with HCV monoinfect...