A common East-Asian ALDH2 mutation causes metabolic disorders and the therapeutic effect of ALDH2 activators - Chang, Yi-Cheng; Lee, Hsiao-Lin; Yang, Wenjin; Hsieh, Meng-Lun; Liu, Cai-Cin; Lee, Tung-Yuan; Huang, Jing-Yong; Nong, Jiun-Yi; Li, Fu-An; Chuang, Hsiao-Li; Ding, Zhi-Zhong; Su, Wei-Lun; et al. (Nature communications, 2023)
Keywords: 13/1; 13/106; 14/63; 4-Hydroxynonenal; 631/154/436/108; 631/208/727/2000; 64/110; 64/60; 692/163/2743/393; 82/16; 82/29; 82/58; 82/80; Acetaldehyde; Acetaldehyde dehydrogenase; Adipose tissue; Adipose tissue (brown); Aldehyde dehydrogenase; Aldehyde dehydrogenase (NAD); Aldehydes; Body fat; Diabetes mellitus (non-insulin dependent); Diet; Electron transport; Electron transport chain; Energy expenditure; Enzymatic activity; Enzymes; Fatty acids; Fatty liver; Glucose; Glucose tolerance; Homeostasis; Humanities and Social Sciences; Insulin resistance; Liver; Males; Metabolic disorders; Mitochondria; multidisciplinary; Mutation; Obesity; Oxidation; Oxidation rate; Proteomics; Science; Science (multidisciplinary); Thermogenesis