Abundance and diversity of mucosa-associated hydrogenotrophic microbes in the healthy human colon

• Published in: The ISME Journal Vol. 6; no. 1; pp. 57 - 70
• Main Authors: Nava, Gerardo M, Carbonero, Franck, Croix, Jennifer A, Greenberg, Eugene, Gaskins, H Rex
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 01.01.2012; Oxford University Press; Nature Publishing Group
• Subjects: Archaea - genetics; Archaea - isolation & purification; Bacteria; Bacteria - genetics; Bacteria - isolation & purification; Biomedical and Life Sciences; Colon - microbiology; Desulfovibrio - genetics; Desulfovibrio - isolation & purification; Ecology; Evolutionary Biology; Female; Genotypes; Gram-Negative Anaerobic Straight, Curved, and Helical Rods - genetics; Gram-Negative Anaerobic Straight, Curved, and Helical Rods - isolation & purification; Humans; Intestinal Mucosa - microbiology; Life Sciences; Male; Metagenome; Methanobacteriaceae - genetics; Methanobacteriaceae - isolation & purification; Microbial Ecology; Microbial Genetics and Genomics; Microbiology; Middle Aged; Original; original-article; Rectum - microbiology; Sulfate reduction; Sulfates; methanogenic archaea; sulfate-reducing bacteria; colonic mucosa; qPCR; T-RFLP

Hydrogenotrophic microbiota have a significant impact on colonic health; however, little is known about their diversity and ecology in situ . Here, molecular-based methods and multivariate analyses were used to examine the abundance and diversity of mucosa-associated hydrogenotrophic microbes in 90...