Molecular characterization of feline caliciviruses isolated from several adult cats with atypical infection showing severe flu-like symptoms on a remote island in Ehime, Japan

• Published in: Virus research Vol. 353; p. 199535
• Main Authors: Nishisaka, Yuki, Fujii, Hikaru, Ono, Fumiko, Kadekaru, Sho, Kogiku, Hiroyuki, Une, Yumi, Takeguchi, Shione, Ohta, Naomi, Eto, Masumi, Takeuchi, Chiharu, Takeuchi, Seigou, Miki, Tetsuko, Tokuda, Akihiko, Ookawa, Keiko, Tohya, Yukinobu, Ishijima, Keita, Okutani, Akiko, Maeda, Ken, Watanabe, Shumpei, Morikawa, Shigeru
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 01.03.2025; Elsevier
• Subjects: adults; Anemia; Animals; Caliciviridae Infections - epidemiology; Caliciviridae Infections - veterinary; Caliciviridae Infections - virology; Calicivirus, Feline - classification; Calicivirus, Feline - genetics; Calicivirus, Feline - isolation & purification; Calicivirus, Feline - pathogenicity; Cat Diseases - epidemiology; Cat Diseases - pathology; Cat Diseases - virology; Cats; diarrhea; Disease Outbreaks - veterinary; disease severity; edema; Feline calicivirus; Feline infectious disease; Female; infectious diseases; Islands; Japan; Japan - epidemiology; Male; mortality; pharynx; Phylogeny; Severe flu-like symptom; Upper respiratory tract disease; viremia; virulence; Virulent systemic feline calicivirus; viruses; VP1; Japan; Virulent systemic feline calicivirus; Anemia; VP1; Feline calicivirus; Severe flu-like symptom; Feline infectious disease; Upper respiratory tract disease

•Epidemic of atypical Feline calicivirus (FCV) in Aoshima Island, Japan.•Adult cats showed severe flu-like symptoms rarely accompanied by anemia and diarrhea.•Aoshima virulent strain likely mutated from typical FCV.•Aoshima virulent strain showed no serological cross-reactivity with an Osaka isolate...