Inhibitory Activities of Samples on Tyrosinases Were Affected by Enzyme Species and Sample Addition Methods
The inhibition of tyrosinase (TYR) activity is an effective measure to inhibit melanin synthesis. At present, there are many methods with discrepant details that study the TYR inhibitory activity of samples. Under the same experimental conditions, this paper systematically studies whether enzyme spe...
Saved in:
Published in | International journal of molecular sciences Vol. 24; no. 7; p. 6013 |
---|---|
Main Authors | , , , , , |
Format | Journal Article |
Language | English |
Published |
Switzerland
MDPI AG
23.03.2023
MDPI |
Subjects | |
Online Access | Get full text |
Cover
Loading…
Abstract | The inhibition of tyrosinase (TYR) activity is an effective measure to inhibit melanin synthesis. At present, there are many methods with discrepant details that study the TYR inhibitory activity of samples. Under the same experimental conditions, this paper systematically studies whether enzyme species and sample addition methods are the key factors that determine the TYR inhibitory activity of samples. TYRs extracted from B16F10 cells, apple and mushroom, called BTYR, ATYR and MTYR, respectively, were selected to implement this study. Results showed that TYR inhibitory activities of samples were obviously affected by the above two factors. It was necessary to select the appropriate enzyme according to the problems to be explained. It was speculated that indirectly inhibitory activity reflected the comprehensive effects of samples on TYR catalytic activity and intracellular TYR synthesis pathway, while directly inhibitory activity reflected the effects of samples on TYR catalytic activity. Additionally, kojic acid could be used as a positive control for both B16F10 cells and MTYR models. The TYR inhibitory activity of β-arbutin was complicated and fickle, while that of epigallocatechin gallate (EGCG) was universal and stable, which is to say, EGCG always inhibited TYR activity in a dose-dependent manner. In conclusion, the TYR inhibitory activities of samples were affected by enzyme species and sample addition methods. Compared with the unstable β-arbutin, EGCG was more valuable for clinical research. |
---|---|
AbstractList | The inhibition of tyrosinase (TYR) activity is an effective measure to inhibit melanin synthesis. At present, there are many methods with discrepant details that study the TYR inhibitory activity of samples. Under the same experimental conditions, this paper systematically studies whether enzyme species and sample addition methods are the key factors that determine the TYR inhibitory activity of samples. TYRs extracted from B16F10 cells, apple and mushroom, called BTYR, ATYR and MTYR, respectively, were selected to implement this study. Results showed that TYR inhibitory activities of samples were obviously affected by the above two factors. It was necessary to select the appropriate enzyme according to the problems to be explained. It was speculated that indirectly inhibitory activity reflected the comprehensive effects of samples on TYR catalytic activity and intracellular TYR synthesis pathway, while directly inhibitory activity reflected the effects of samples on TYR catalytic activity. Additionally, kojic acid could be used as a positive control for both B16F10 cells and MTYR models. The TYR inhibitory activity of β-arbutin was complicated and fickle, while that of epigallocatechin gallate (EGCG) was universal and stable, which is to say, EGCG always inhibited TYR activity in a dose-dependent manner. In conclusion, the TYR inhibitory activities of samples were affected by enzyme species and sample addition methods. Compared with the unstable β-arbutin, EGCG was more valuable for clinical research. |
Audience | Academic |
Author | Zhang, Jianyong Wang, Weiwei Engelhardt, Ulrich H Wang, Wei Yang, Lijuan Jiang, Heyuan |
AuthorAffiliation | 2 College of Horticulture, Fujian Agriculture and Forestry University, Fuzhou 350002, China 1 Key Laboratory of Biology, Genetics and Breeding of Special Economic Animals and Plants, Ministry of Agriculture and Rural Affairs, Tea Research Institute, Chinese Academy of Agricultural Sciences, 9 Meiling South Road, Xihu District, Hangzhou 310008, China; ww1040491839@163.com (W.W.) 3 Institute of Food Chemistry, Technischen Universität Braunschweig, Schleinitzstr. 20, 38106 Braunschweig, Germany |
AuthorAffiliation_xml | – name: 2 College of Horticulture, Fujian Agriculture and Forestry University, Fuzhou 350002, China – name: 1 Key Laboratory of Biology, Genetics and Breeding of Special Economic Animals and Plants, Ministry of Agriculture and Rural Affairs, Tea Research Institute, Chinese Academy of Agricultural Sciences, 9 Meiling South Road, Xihu District, Hangzhou 310008, China; ww1040491839@163.com (W.W.) – name: 3 Institute of Food Chemistry, Technischen Universität Braunschweig, Schleinitzstr. 20, 38106 Braunschweig, Germany |
Author_xml | – sequence: 1 givenname: Wei orcidid: 0000-0002-7713-9276 surname: Wang fullname: Wang, Wei organization: College of Horticulture, Fujian Agriculture and Forestry University, Fuzhou 350002, China – sequence: 2 givenname: Lijuan surname: Yang fullname: Yang, Lijuan organization: Key Laboratory of Biology, Genetics and Breeding of Special Economic Animals and Plants, Ministry of Agriculture and Rural Affairs, Tea Research Institute, Chinese Academy of Agricultural Sciences, 9 Meiling South Road, Xihu District, Hangzhou 310008, China – sequence: 3 givenname: Weiwei surname: Wang fullname: Wang, Weiwei organization: Key Laboratory of Biology, Genetics and Breeding of Special Economic Animals and Plants, Ministry of Agriculture and Rural Affairs, Tea Research Institute, Chinese Academy of Agricultural Sciences, 9 Meiling South Road, Xihu District, Hangzhou 310008, China – sequence: 4 givenname: Jianyong surname: Zhang fullname: Zhang, Jianyong organization: Key Laboratory of Biology, Genetics and Breeding of Special Economic Animals and Plants, Ministry of Agriculture and Rural Affairs, Tea Research Institute, Chinese Academy of Agricultural Sciences, 9 Meiling South Road, Xihu District, Hangzhou 310008, China – sequence: 5 givenname: Ulrich H surname: Engelhardt fullname: Engelhardt, Ulrich H organization: Institute of Food Chemistry, Technischen Universität Braunschweig, Schleinitzstr. 20, 38106 Braunschweig, Germany – sequence: 6 givenname: Heyuan orcidid: 0000-0002-3101-7951 surname: Jiang fullname: Jiang, Heyuan organization: Key Laboratory of Biology, Genetics and Breeding of Special Economic Animals and Plants, Ministry of Agriculture and Rural Affairs, Tea Research Institute, Chinese Academy of Agricultural Sciences, 9 Meiling South Road, Xihu District, Hangzhou 310008, China |
BackLink | https://www.ncbi.nlm.nih.gov/pubmed/37046986$$D View this record in MEDLINE/PubMed |
BookMark | eNpdUk1vEzEQXaEi-gE3zmglLhyaYnvXa-8JrapSIhVxaBFHy2uPE4ddO9ibSuHXMyGhSpEPHo_fe-MZv_PiJMQARfGWkquqaslHvxozq4loCK1eFGe0ZmxGSCNOjuLT4jznFSGsYrx9VZxWgtRNK5uz4uc8LH3vp5i2ZWcm_-gnD7mMrrzX43rYhaF82KaYfdAZjz8gQdk5B2YCW_bb8ib83o5Q3q_B7Jg62AO17KxFNeR_hWkZbX5dvHR6yPDmsF8U3z_fPFx_md19u51fd3czw6mcZr1snGPYEOOcQy-1tEZQwbnjsqkl64nrKwPGQt9bKmvWOuDMNq7htWDOVRfFfK9ro16pdfKjTlsVtVd_EzEtlE6TNwMonAJIyp12VNTSSO2AiB6rAk4NK6LWp73WetOPYA2EKenhmejzm-CXahEfFSWkrWTNUeHDQSHFXxvIkxp9NjAMOkDcZMUk_hCTrSQIff8fdBU3KeCsFBNt2wgp2xpRV3vUQmMHPriIhQ0uC6M3aA7nMd8JTlvGBaNIuNwTDH5jTuCenk-J2nlIHXsI4e-OW34C_zNN9Qe7kcUB |
CitedBy_id | crossref_primary_10_3390_ddc3020025 |
Cites_doi | 10.1111/j.1600-0749.1998.tb00731.x 10.1016/S0924-2244(00)89054-8 10.3390/molecules26040964 10.1021/jf011378z 10.1248/cpb.51.798 10.1248/bpb.27.510 10.1111/j.1600-0749.1998.tb00705.x 10.1021/jf020826f 10.1080/14756366.2016.1256882 10.1007/s12010-009-8730-9 10.1021/acs.jnatprod.8b00847 10.1042/BJ20080892 10.3390/ijms232314922 10.1016/j.ejmech.2021.113850 10.1021/acs.jmedchem.0c00994 10.1016/j.ijbiomac.2018.10.046 10.1016/j.foodchem.2021.130241 10.1016/S0021-9258(18)71485-3 10.1371/journal.pone.0109398 10.1016/j.ab.2006.01.011 10.1007/s12230-014-9396-6 10.1080/14756366.2018.1545767 10.1271/bbb.59.143 10.1016/S0014-5793(00)01609-4 10.1016/j.jid.2018.01.019 10.1080/07391102.2012.682211 10.1021/acs.jafc.0c07379 10.1002/bab.2166 10.1021/acs.jafc.1c07028 10.3390/antiox11030502 10.1016/j.foodchem.2019.125310 10.3390/ijms232416021 10.1016/0005-2744(80)90061-3 10.1016/j.bmc.2004.07.050 |
ContentType | Journal Article |
Copyright | COPYRIGHT 2023 MDPI AG 2023 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. 2023 by the authors. 2023 |
Copyright_xml | – notice: COPYRIGHT 2023 MDPI AG – notice: 2023 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. – notice: 2023 by the authors. 2023 |
DBID | CGR CUY CVF ECM EIF NPM AAYXX CITATION 3V. 7X7 7XB 88E 8FI 8FJ 8FK 8G5 ABUWG AFKRA AZQEC BENPR CCPQU DWQXO FYUFA GHDGH GNUQQ GUQSH K9. M0S M1P M2O MBDVC PIMPY PQEST PQQKQ PQUKI PRINS Q9U 7X8 5PM DOA |
DOI | 10.3390/ijms24076013 |
DatabaseName | Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed CrossRef ProQuest Central (Corporate) Health & Medical Collection ProQuest Central (purchase pre-March 2016) Medical Database (Alumni Edition) Hospital Premium Collection Hospital Premium Collection (Alumni Edition) ProQuest Central (Alumni) (purchase pre-March 2016) Research Library (Alumni Edition) ProQuest Central (Alumni) ProQuest Central ProQuest Central Essentials ProQuest Central ProQuest One Community College ProQuest Central Korea Health Research Premium Collection Health Research Premium Collection (Alumni) ProQuest Central Student Research Library Prep ProQuest Health & Medical Complete (Alumni) Health & Medical Collection (Alumni Edition) Medical Database Research Library Research Library (Corporate) Publicly Available Content Database ProQuest One Academic Eastern Edition (DO NOT USE) ProQuest One Academic ProQuest One Academic UKI Edition ProQuest Central China ProQuest Central Basic MEDLINE - Academic PubMed Central (Full Participant titles) DOAJ Directory of Open Access Journals |
DatabaseTitle | MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid) CrossRef Publicly Available Content Database Research Library Prep ProQuest Central Student ProQuest Central Essentials ProQuest Health & Medical Complete (Alumni) ProQuest Central (Alumni Edition) ProQuest One Community College Research Library (Alumni Edition) ProQuest Central China ProQuest Central Health Research Premium Collection Health and Medicine Complete (Alumni Edition) ProQuest Central Korea ProQuest Research Library ProQuest Medical Library (Alumni) ProQuest Central Basic ProQuest One Academic Eastern Edition ProQuest Hospital Collection Health Research Premium Collection (Alumni) ProQuest Hospital Collection (Alumni) ProQuest Health & Medical Complete ProQuest Medical Library ProQuest One Academic UKI Edition ProQuest One Academic ProQuest Central (Alumni) MEDLINE - Academic |
DatabaseTitleList | Publicly Available Content Database CrossRef MEDLINE |
Database_xml | – sequence: 1 dbid: DOA name: DOAJ Directory of Open Access Journals url: https://www.doaj.org/ sourceTypes: Open Website – sequence: 2 dbid: NPM name: PubMed url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 3 dbid: EIF name: MEDLINE url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search sourceTypes: Index Database – sequence: 4 dbid: BENPR name: ProQuest Central url: https://www.proquest.com/central sourceTypes: Aggregation Database |
DeliveryMethod | fulltext_linktorsrc |
Discipline | Biology |
EISSN | 1422-0067 |
ExternalDocumentID | oai_doaj_org_article_469e815faf1748c8afe07b5ebe06755f A751925721 10_3390_ijms24076013 37046986 |
Genre | Journal Article |
GeographicLocations | China |
GeographicLocations_xml | – name: China |
GrantInformation_xml | – fundername: Science and Technology Innovation Project of Chinese Academy of Agricultural Sciences grantid: CAAS-ASTIP-2023-TRICAAS – fundername: National Natural Science Foundation of China grantid: 31670692 – fundername: Basic Scientific Research Project of Chinese Academy of Agricultural Sciences grantid: Y2021GH06 |
GroupedDBID | --- 29J 2WC 3V. 53G 5GY 5VS 7X7 88E 8FE 8FG 8FH 8FI 8FJ 8G5 A8Z AADQD AAFWJ ABDBF ABJCF ABUWG ACGFO ACIHN ACIWK ACPRK ADBBV AEAQA AENEX AFKRA AFPKN AFZYC ALMA_UNASSIGNED_HOLDINGS AOIJS AZQEC BAWUL BBNVY BCNDV BENPR BHPHI BPHCQ BVXVI CCPQU CGR CS3 CUY CVF D1I DIK DU5 DWQXO E3Z EBD EBS ECM EIF EJD ESTFP ESX F5P FRP FYUFA GNUQQ GROUPED_DOAJ GUQSH GX1 HCIFZ HH5 HMCUK HYE IAO ITC KB. KQ8 LK8 M1P M2O M48 M7P MODMG M~E NPM O5R O5S OK1 P2P PDBOC PIMPY PQQKQ PROAC PSQYO RIG RNS RPM TR2 TUS UKHRP ~8M AAHBH AAYXX ALIPV CITATION BGLVJ 7XB 8FK K9. MBDVC PQEST PQUKI PRINS Q9U 7X8 5PM |
ID | FETCH-LOGICAL-c518t-b86ff20762555eb8a8dc71755f586482b0fb3cecdebbd18429fe52d6f65472ff3 |
IEDL.DBID | RPM |
ISSN | 1422-0067 1661-6596 |
IngestDate | Fri Jul 05 11:21:32 EDT 2024 Tue Sep 17 21:32:50 EDT 2024 Fri Jun 28 13:50:56 EDT 2024 Fri Sep 13 07:46:06 EDT 2024 Fri Feb 02 04:17:25 EST 2024 Fri Aug 23 01:59:02 EDT 2024 Thu May 23 23:31:07 EDT 2024 |
IsDoiOpenAccess | true |
IsOpenAccess | true |
IsPeerReviewed | true |
IsScholarly | true |
Issue | 7 |
Keywords | sample addition methods kojic acid tyrosinase species β-arbutin EGCG |
Language | English |
License | Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
LinkModel | DirectLink |
MergedId | FETCHMERGED-LOGICAL-c518t-b86ff20762555eb8a8dc71755f586482b0fb3cecdebbd18429fe52d6f65472ff3 |
Notes | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
ORCID | 0000-0002-7713-9276 0000-0002-3101-7951 |
OpenAccessLink | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10093845/ |
PMID | 37046986 |
PQID | 2799678894 |
PQPubID | 2032341 |
ParticipantIDs | doaj_primary_oai_doaj_org_article_469e815faf1748c8afe07b5ebe06755f pubmedcentral_primary_oai_pubmedcentral_nih_gov_10093845 proquest_miscellaneous_2800628980 proquest_journals_2799678894 gale_infotracacademiconefile_A751925721 crossref_primary_10_3390_ijms24076013 pubmed_primary_37046986 |
PublicationCentury | 2000 |
PublicationDate | 20230323 |
PublicationDateYYYYMMDD | 2023-03-23 |
PublicationDate_xml | – month: 3 year: 2023 text: 20230323 day: 23 |
PublicationDecade | 2020 |
PublicationPlace | Switzerland |
PublicationPlace_xml | – name: Switzerland – name: Basel |
PublicationTitle | International journal of molecular sciences |
PublicationTitleAlternate | Int J Mol Sci |
PublicationYear | 2023 |
Publisher | MDPI AG MDPI |
Publisher_xml | – name: MDPI AG – name: MDPI |
References | Tudela (ref_34) 2006; 351 Shi (ref_38) 2010; 160 Sun (ref_10) 2016; 32 Mayr (ref_1) 2019; 82 Pillaiyar (ref_17) 2017; 32 Roulier (ref_24) 2020; 63 Shen (ref_26) 2020; 18 Liu (ref_27) 1995; 18 Zolghadri (ref_7) 2019; 34 ref_13 ref_12 ref_11 Chen (ref_20) 2022; 69 Sugimoto (ref_28) 2004; 27 ref_31 Bubacco (ref_3) 2000; 474 Zhao (ref_4) 2019; 35 Chakraborty (ref_29) 1998; 11 Gregus (ref_25) 1988; 244 Funayama (ref_14) 1995; 59 ref_16 Carcelli (ref_8) 2020; 303 Hearing (ref_23) 1980; 611 Wang (ref_39) 2012; 30 He (ref_21) 2021; 362 Chen (ref_36) 2002; 50 Martinez (ref_6) 1995; 6 Wang (ref_19) 2022; 70 Nakajima (ref_30) 1998; 11 Seo (ref_5) 2003; 51 ref_40 Tudela (ref_35) 2008; 416 Sugimoto (ref_15) 2003; 51 Fu (ref_18) 2021; 226 Mann (ref_22) 2018; 138 Hou (ref_41) 2014; 91 ref_9 Kupper (ref_2) 1989; 264 Xu (ref_32) 2021; 69 Kubo (ref_37) 2004; 12 Xiong (ref_33) 2019; 121 |
References_xml | – volume: 11 start-page: 206 year: 1998 ident: ref_29 article-title: Effect of arbutin on melanogenic proteins in human melanocytes publication-title: Pigm. Cell Melanoma Res. doi: 10.1111/j.1600-0749.1998.tb00731.x contributor: fullname: Chakraborty – volume: 6 start-page: 195 year: 1995 ident: ref_6 article-title: The biochemistry and control of enzymatic browning publication-title: Trends Food Sci. Technol. doi: 10.1016/S0924-2244(00)89054-8 contributor: fullname: Martinez – ident: ref_9 – ident: ref_11 doi: 10.3390/molecules26040964 – volume: 50 start-page: 4108 year: 2002 ident: ref_36 article-title: Kinetics of mushroom tyrosinase inhibition by quercetin publication-title: J. Agric. Food Chem. doi: 10.1021/jf011378z contributor: fullname: Chen – volume: 32 start-page: 345 year: 2016 ident: ref_10 article-title: Research progress on the mechanisms of tyrosinase catalyzed reactions publication-title: J. Ludong Univ. (Nat. Sci. Ed.) contributor: fullname: Sun – volume: 51 start-page: 798 year: 2003 ident: ref_15 article-title: Syntheses of arbutin-alpha-glycosides and a comparison of their inhibitory effects with those of alpha-arbutin and arbutin on human tyrosinase publication-title: Chem. Pharm. Bull. doi: 10.1248/cpb.51.798 contributor: fullname: Sugimoto – volume: 27 start-page: 510 year: 2004 ident: ref_28 article-title: Inhibitory effects of alpha-arbutin on melanin synthesis in cultured human melanoma cells and a three-dimensional human skin model publication-title: Biol. Pharm. Bull. doi: 10.1248/bpb.27.510 contributor: fullname: Sugimoto – volume: 11 start-page: 12 year: 1998 ident: ref_30 article-title: Arbutin increases the pigmentation of cultured human melanocytes through mechanisms other than the induction of tyrosinase activity publication-title: Pigm. Cell Melanoma Res. doi: 10.1111/j.1600-0749.1998.tb00705.x contributor: fullname: Nakajima – volume: 35 start-page: 1633 year: 2019 ident: ref_4 article-title: Research progress in melanogenesis signaling pathway publication-title: Chin. J. Biotechnol. contributor: fullname: Zhao – volume: 51 start-page: 2837 year: 2003 ident: ref_5 article-title: Mushroom tyrosinase: Recent prospects publication-title: J. Agric. Food Chem. doi: 10.1021/jf020826f contributor: fullname: Seo – volume: 32 start-page: 403 year: 2017 ident: ref_17 article-title: Skin whitening agents: Medicinal chemistry perspective of tyrosinase inhibitors publication-title: J. Enzyme Inhib. Med. Chem. doi: 10.1080/14756366.2016.1256882 contributor: fullname: Pillaiyar – volume: 160 start-page: 1896 year: 2010 ident: ref_38 article-title: The effect of trifluoroethanol on tyrosinase activity and conformation: Inhibition kinetics and computational simulations publication-title: Appl. Biochem. Biotechnol. doi: 10.1007/s12010-009-8730-9 contributor: fullname: Shi – volume: 82 start-page: 136 year: 2019 ident: ref_1 article-title: Mushroom tyrosinase-based enzyme inhibition assays are not suitable for bioactivity-guided fractionation of extracts publication-title: J. Nat. Prod. doi: 10.1021/acs.jnatprod.8b00847 contributor: fullname: Mayr – volume: 416 start-page: 431 year: 2008 ident: ref_35 article-title: Phenolic substrates and suicide inactivation of tyrosinase: Kinetics and mechanism publication-title: Biochem. J. doi: 10.1042/BJ20080892 contributor: fullname: Tudela – ident: ref_13 doi: 10.3390/ijms232314922 – volume: 226 start-page: 113850 year: 2021 ident: ref_18 article-title: Design, synthesis and biological evaluation of tyrosinase-targeting PROTACs publication-title: Eur. J. Med. Chem. doi: 10.1016/j.ejmech.2021.113850 contributor: fullname: Fu – volume: 63 start-page: 13428 year: 2020 ident: ref_24 article-title: Advances in the design of genuine human tyrosinase inhibitors for targeting melanogenesis and related pigmentations publication-title: J. Med. Chem. doi: 10.1021/acs.jmedchem.0c00994 contributor: fullname: Roulier – volume: 121 start-page: 463 year: 2019 ident: ref_33 article-title: The inhibitory effect of pyrogallol on tyrosinase activity and structure: Integration study of inhibition kinetics with molecular dynamics simulation publication-title: Int. J. Biol. Macromol. doi: 10.1016/j.ijbiomac.2018.10.046 contributor: fullname: Xiong – volume: 18 start-page: 14 year: 1995 ident: ref_27 article-title: An in vitro study of cortex sophorae extract on intestine and uterus muscles of animals publication-title: J. Jining Med. Coll. contributor: fullname: Liu – volume: 362 start-page: 130241 year: 2021 ident: ref_21 article-title: Design, synthesis, molecular modeling, and biological evaluation of novel kojic acid derivatives containing bioactive heterocycle moiety as inhibitors of tyrosinase and antibrowning agents publication-title: Food Chem. doi: 10.1016/j.foodchem.2021.130241 contributor: fullname: He – volume: 264 start-page: 17250 year: 1989 ident: ref_2 article-title: Isolation and characterization of the tyrosinase gene from Neurospora crassa publication-title: J. Biol. Chem. doi: 10.1016/S0021-9258(18)71485-3 contributor: fullname: Kupper – ident: ref_40 doi: 10.1371/journal.pone.0109398 – volume: 351 start-page: 128 year: 2006 ident: ref_34 article-title: Calculating molar absorptivities for quinones: Application to the measurement of tyrosinase activity publication-title: Anal. Biochem. doi: 10.1016/j.ab.2006.01.011 contributor: fullname: Tudela – ident: ref_31 – volume: 91 start-page: 655 year: 2014 ident: ref_41 article-title: Effects of curing treatment on the browning of fresh-cut potatoes publication-title: Am. J. Potato Res. doi: 10.1007/s12230-014-9396-6 contributor: fullname: Hou – volume: 34 start-page: 279 year: 2019 ident: ref_7 article-title: A comprehensive review on tyrosinase inhibitors publication-title: J. Enzyme Inhib. Med. Chem. doi: 10.1080/14756366.2018.1545767 contributor: fullname: Zolghadri – volume: 244 start-page: 91 year: 1988 ident: ref_25 article-title: Species variation in toxication and detoxication of acetaminophen in vivo: A comparative study of biliary and urinary excretion of acetaminophen metabolites publication-title: J. Pharmacol. Exp. Ther. contributor: fullname: Gregus – volume: 18 start-page: 152 year: 2020 ident: ref_26 article-title: Effect of species difference of experimental animals on traditional chinese medicine research publication-title: Chin. Med. Mod. Distance Educ. China contributor: fullname: Shen – volume: 59 start-page: 143 year: 1995 ident: ref_14 article-title: Effects of alpha- and beta-arbutin on activity of tyrosinases from mushroom and mouse melanoma publication-title: Biosci. Biotechnol. Biochem. doi: 10.1271/bbb.59.143 contributor: fullname: Funayama – volume: 474 start-page: 228 year: 2000 ident: ref_3 article-title: EPR study of the dinuclear active copper site of tyrosinase from Streptomyces antibioticus publication-title: FEBS Lett. doi: 10.1016/S0014-5793(00)01609-4 contributor: fullname: Bubacco – volume: 138 start-page: 1601 year: 2018 ident: ref_22 article-title: Inhibition of human tyrosinase requires molecular motifs distinctively different from mushroom tyrosinase publication-title: J. Investig. Dermatol. doi: 10.1016/j.jid.2018.01.019 contributor: fullname: Mann – volume: 30 start-page: 460 year: 2012 ident: ref_39 article-title: The effect of fucoidan on tyrosinase: Computational molecular dynamics integrating inhibition kinetics publication-title: J. Biomol. Struct. Dyn. doi: 10.1080/07391102.2012.682211 contributor: fullname: Wang – volume: 69 start-page: 4243 year: 2021 ident: ref_32 article-title: Antityrosinase mechanism and antimelanogenic effect of arbutin esters synthesis catalyzed by whole-cell biocatalyst publication-title: J. Agric. Food Chem. doi: 10.1021/acs.jafc.0c07379 contributor: fullname: Xu – volume: 69 start-page: 951 year: 2022 ident: ref_20 article-title: Evaluation of antityrosinase activity and mechanism, antioxidation, and UV filter properties of theaflavin publication-title: Biotechnol. Appl. Biochem. doi: 10.1002/bab.2166 contributor: fullname: Chen – volume: 70 start-page: 1304 year: 2022 ident: ref_19 article-title: Effect of active groups and oxidative dimerization on the antimelanogenic activity of catechins and their dimeric oxidation products publication-title: J. Agric. Food Chem. doi: 10.1021/acs.jafc.1c07028 contributor: fullname: Wang – ident: ref_16 doi: 10.3390/antiox11030502 – volume: 303 start-page: 125310 year: 2020 ident: ref_8 article-title: Hydroxyphenyl thiosemicarbazones as inhibitors of mushroom tyrosinase and antibrowning agents publication-title: Food Chem. doi: 10.1016/j.foodchem.2019.125310 contributor: fullname: Carcelli – ident: ref_12 doi: 10.3390/ijms232416021 – volume: 611 start-page: 251 year: 1980 ident: ref_23 article-title: Mammalin tyrosinase. Stoichiometry and measurement of reaction products publication-title: Biochim. Biophys. Acta. doi: 10.1016/0005-2744(80)90061-3 contributor: fullname: Hearing – volume: 12 start-page: 5343 year: 2004 ident: ref_37 article-title: Oxidation products of quercetin catalyzed by mushroom tyrosinase publication-title: Bioorg. Med. Chem. doi: 10.1016/j.bmc.2004.07.050 contributor: fullname: Kubo |
SSID | ssj0023259 |
Score | 2.4141123 |
Snippet | The inhibition of tyrosinase (TYR) activity is an effective measure to inhibit melanin synthesis. At present, there are many methods with discrepant details... |
SourceID | doaj pubmedcentral proquest gale crossref pubmed |
SourceType | Open Website Open Access Repository Aggregation Database Index Database |
StartPage | 6013 |
SubjectTerms | Acids Agaricales Analysis Arbutin - pharmacology Biosynthesis Catalytic activity Catechin Cell culture EGCG Enzyme Inhibitors - pharmacology Enzymes Epigallocatechin gallate Fruits Kojic acid Melanin Melanins - metabolism Melanoma Methods Monophenol Monooxygenase - metabolism Physiology Research methodology sample addition methods Skin cancer species Tyrosinase β-arbutin |
SummonAdditionalLinks | – databaseName: DOAJ Directory of Open Access Journals dbid: DOA link: http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwrV1La9wwEBYlUOil9F23aVChpScTW28f3ZKQBNJLE5qb0JO4JdqQ3Ry2v74j2bus6SGX3oxlI3lmpJnPGs2H0Kc2Mmk7yupGelUzy0VtwIvUgjvLrewghMgHnM-_i5NLdnbFr3aovnJO2FgeeBTcIcC3oFoeTYTYWTllYmik5dB3jnV5LKtvyzdgaoJalBSatBa8D3TbiTHlnQLAPxx-3SwzjAEkQmfOqNTs_3dl3nFN87TJHT90_Aw9nQJI3I8Df44ehfQCPR4pJdcv0e_TdD3YIW-d494VagjAwngR8Q-TCwHDZcIXaxjOkMCBLfHPcBdwX7I6gsd2jY_Sn_VNwIWYHtpN8tOruPe-JHjh80I7vXyFLo-PLr6d1BOhQu14q1a1VSJGAp8OOAIkqIzyDuAcSJErwRSxTbTUBeeDtR6gH-li4MSLmBmKSYz0NdpLixTeIgwKlZR0jaXKsNZ2ShSsSx1xwTBuK_R5I1l9O9bN0IA3sgb0rgYq9DWLfftMrnZdboAN6MkG9EM2UKEvWWk6z0nQjDPT0QIYaq5upXsJcSqsTaSt0P5Gr3qarEtNJIA-qVTHKvRx2wzTLO-dmBQW9_CMKqdNO9VU6M1oBtsxU1l4OEWF1MxAZh81b0nDdSnl3eY_Sorxd_9DDO_REwKmnzPkCN1He6u7-_ABQqaVPSiz4y_gUBQg priority: 102 providerName: Directory of Open Access Journals – databaseName: ProQuest Central dbid: BENPR link: http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV1Lb9QwELZKKyQuiDeBgowE4hTtxo4T54RStNWC1ApBK3qL_GwDqlN2t4fl1zPjZJeNkLhFcSKNPWPPfPZ4PkLeZj4vdcXzdFpameZaFKkCL5IWwmihywpCCLzgfHJazM_zzxfiYo_MN3dhMK1ysybGhdp2BvfIJ6yEyBzwWpVPlMZdALOafLj5lSJ_FJ6zDmQad8gBy3I8sD04mp1--boFX5xF4rQM_BEIUhV9EjwHyD9pf1wvEdgANuEj9xSr-P-7Vu84q3Ei5Y5nOn5A7g8hJa17G3hI9lx4RO72JJPrx-Tnp3DV6hYP02ltIlkEoGPaefpNYWlgeAz0bA3itAFc2pJ-dwtH65jn4SzVazoLv9fXjkaqemhXwQ6_0tramPJFTyIR9fIJOT-enX2cpwPFQmpEJleploX3DLoOyEI4LZW0BgCeEF7IIpdMT73mxhnrtLYABlnlnWC28MhZzLznT8l-6IJ7TiiouOSsmmouVZ7pShYR_XLDjFO50Al5txnZ5qavpNEAAkENNLsaSMgRDvv2G6x_HV90i8tmmE4NgHonM-GVB0QljVTeTUsNPXCIgIRPyHtUWoOzFG1FDZcNQFSsd9XUJUSusFqxLCGHG702w_RdNn-NLSFvts0w8fA0RQXX3cI3Mt4_reQ0Ic96M9jKzMvIzFkkRI4MZNSpcUtor2Jx7wz3mGQuXvxfrpfkHhLfYzYc44dkf7W4da8gPFrp14Pl_wE9mhBW priority: 102 providerName: ProQuest – databaseName: Scholars Portal Open Access Journals dbid: M48 link: http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1Lb9QwEB6VIiQuiDeBgowE4hRI_EicA0IBtSpIy4Wu6C2yHbsNUC_sbiXCr2fsZFcblRO3KLYl2zOTmS8ezwfwIne81BXjaVa2MuVaFKlCL5IWwmihywpDiHDBefa5OJ7zT6fidA82bKPjBq7-Ce0Cn9R8-eP171_9OzT4twFxImR_0327WAVggtiCXYPrlDMedH3Gt-cJGDaIakh7vzJi4pBi3f6rX-cd9zRNndzxRUe34dYYRJJ6kPod2LP-LtwYaCX7e_D9oz_vdBeOz0ltIj0E4mGycOSLCsWA8dGTkx6n03l0Yivy1S4tqWNmh22J7smh_9NfWBLJ6bFd-XYcSuq2jUleZBapp1f3YX50ePLhOB1JFVIjcrlOtSyco7h0xBLCaqlkaxDSCeGELLikOnOaGWtaq3WL8I9WzgraFi6wFFPn2APY9wtvHwFBoZaMVplmUvFcV7KIeJcZaqziQifwcrOzzc-hdkaDmCNIoNmVQALvw7Zv-4SK1_HFYnnWjAbUIIy3MhdOOcRQ0kjlbFZqXIENmEe4BF4FoTVBU1AyRo3XC3CqocJVU5cYq-L3ieYJHGzk2mz0raElAr9Syoon8HzbjKYWzk-Ut4tL7CPjjdNKZgk8HNRgO2dWRi7OIgE5UZDJoqYtvjuP5bzz8FdJcvH4_4c-gZsUlTzkxlF2APvr5aV9isHSWj-LdvAXF-EXmg priority: 102 providerName: Scholars Portal |
Title | Inhibitory Activities of Samples on Tyrosinases Were Affected by Enzyme Species and Sample Addition Methods |
URI | https://www.ncbi.nlm.nih.gov/pubmed/37046986 https://www.proquest.com/docview/2799678894/abstract/ https://search.proquest.com/docview/2800628980 https://pubmed.ncbi.nlm.nih.gov/PMC10093845 https://doaj.org/article/469e815faf1748c8afe07b5ebe06755f |
Volume | 24 |
hasFullText | 1 |
inHoldings | 1 |
isFullTextHit | |
isPrint | |
link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnZ3db9MwEMBP2xASL4hvAiMyEoinrE1sJ85jNrUMpE4TbKJvUezYW4C6U9s9lL-es5NUjXjjJYriRLJzvtz94vMdwIfYsEzmlEXjrBYRkzyNKrQiUcqV5DLL0YVwG5xnF-n5Nfs65_MDSPu9MD5oX8nmxP5enNjm1sdW3i3UqI8TG13OzmLH4YLx0SEcZpT2jN5hFkWPvg1xpwj0o-bnYu2wBcmDDoyPz9H_75d4zxQNwyT37M70CTzuHEZStB17CgfaPoOHbQnJ7XP49cXeNrJxS-WkUL4UBLIvWRryvXKJf_HUkqstdqexaLDW5IdeaVL4KA5dE7klE_tnu9DEF6LH9srW3aOkqGsf0EVmvsz0-gVcTydXZ-dRV0AhUjwWm0iK1JgEh47cwLUUlagV4hvnhouUiUSOjaRKq1pLWSPqJbnRPKlT4yoSJ8bQl3Bkl1a_BoICzGiSjyUVFYtlLlLPtlQlSleMywA-9m-2vGvzZJTIF04C5b4EAjh1r313j8tu7S8sVzdlJ-MSkV2LmJvKIC8JJSqjx5nEEWjHN9wE8MkJrXQ6iJJRVbeVALvqslmVRYZ-KX6LkjiA416uZaec6zLJEPIQ_XMWwPtdM6qVWyuprF7e4z3C7y7NxTiAV-002PWZZr7uZhqAGEyQwaCGLTiTferufua--f9H38IjV_LexcEl9BiONqt7_Q4do40MURvmGR7F9HMID04nF5ffQv-TIXQGi-NxxkToteUvWpYW3Q |
link.rule.ids | 230,315,733,786,790,870,891,2115,2236,12083,12792,21416,24346,27957,27958,31754,31755,33408,33409,33779,33780,43345,43635,43840,53827,53829,74102,74392,74659 |
linkProvider | National Library of Medicine |
linkToHtml | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV1Lb9QwELagCMEF8SZQwEggTlETPxLnhAJqtYVuL2zF3izbsduA6pTN9rD8esZOdrsrJG5R7Ci2x-OZzx7Ph9D73LFSV5SlWdmIlGlepAqsSFpwo7kuK3AhwgXn6WkxOWNf53w-brj1Y1jlek2MC3XTmbBHfkBK8MwBr1Xs09XvNLBGhdPVkULjNrrDKGUhpK-c3wAuSiJZWg42CH5eFUPgOwWYf9D-vOwDmAE8QndMUszc_-_6vGWgdoMnt6zR0UP0YHQjcT3I_RG6Zf1jdHcgllw9Qb-O_UWr23CAjmsTCSIAEePO4e8qpAOGR49nK2hO68GM9fiHXVhcx9gO22C9wof-z-rS4khPD-XKN-OnuG6aGOaFp5F8un-Kzo4OZ18m6UirkBqei2WqReEcga4DmuBWCyUaA6COc8dFwQTRmdPUWNNYrRsAgKRylpOmcIGnmDhHn6E933n7AmEQa0lJlWkqFMt1JYqIeKkhxirGdYI-rEdWXg3ZMySgjiABuS2BBH0Ow76pE3Jexxfd4lyOKiQByFuRc6ccoChhhHI2KzX0wAbUw12CPgahyaCZIBmjxgsG0NSQ40rWJXirsEKRPEH7a7nKUWV7eTPBEvRuUwzKFk5QlLfdNdQR8c5pJbIEPR-mwabNtIxsnEWCxM4E2enUbolvL2JC7zzsKwnGX_6_XW_RvclseiJPjk-_vUL3A_F9iIYjdB_tLRfX9jW4R0v9JurAX7nNDiM |
linkToPdf | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV1Lb9QwELagCMQF8SZQwEggTtEmdpw4JxSgqxZohUQr9mbFL5pWdcpme1h-PWPHu90VErcoTqRxZsYzXzyeD6G3uS0qWdMizSrN00KyMm0hiqQlU5LJqoYUwh9wPjwq90-KLzM2i_VPQyyrXK2JYaHWvfL_yCekgswc8FpdTGwsi_j-efrh8nfqGaT8Tmuk07iJbkGUzDybQTW7Bl-UBOK0HOIRCFKXYxE8Bcg_6c4uBg9sAJvQrfAUuvj_u1ZvBKvtQsqNyDS9j-7FlBI3ow08QDeMe4hujySTy0fo_MCddrLzm-m4UYEsAtAx7i3-0frWwHDp8PESxOkchLQB_zRzg5tQ52E0lku85_4sLwwOVPUw3jodX8WN1qHkCx8GIurhMTqZ7h1_2k8jxUKqWM4XqeSltQSmDsiCGclbrhUAPMYs42XBicyspMoobaTUAAZJbQ0jurSes5hYS5-gHdc78wxhUHFFSZ1JytsilzUvA_qliijTFkwm6N3qy4rLsZOGAATiNSA2NZCgj_6zr5_x_a_DjX7-S0R3EgDqDc-ZbS0gKq54a01WSZiB8QiI2QS990oT3ktBM6qNhw1AVN_vSjQVZK6wWpE8QbsrvYrovoO4NrYEvVkPg-P53ZTWmf4KnuHh_GnNswQ9Hc1gLTOtAjNnmSC-ZSBbk9oecd1paO6d-39MvGDP_y_Xa3QHzF98Ozj6-gLdJWDfvjCO0F20s5hfmZeQKS3kq-ACfwFGtRJP |
openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Inhibitory+Activities+of+Samples+on+Tyrosinases+Were+Affected+by+Enzyme+Species+and+Sample+Addition+Methods&rft.jtitle=International+journal+of+molecular+sciences&rft.au=Wang%2C+Wei&rft.au=Yang%2C+Lijuan&rft.au=Wang%2C+Weiwei&rft.au=Zhang%2C+Jianyong&rft.date=2023-03-23&rft.pub=MDPI&rft.eissn=1422-0067&rft.volume=24&rft.issue=7&rft_id=info:doi/10.3390%2Fijms24076013&rft.externalDBID=PMC10093845 |
thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=1422-0067&client=summon |
thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=1422-0067&client=summon |
thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=1422-0067&client=summon |