Progression of Intermediate Age-related Macular Degeneration with Proliferation and Inner Retinal Migration of Hyperreflective Foci

• Published in: Ophthalmology (Rochester, Minn.) Vol. 120; no. 5; pp. 1038 - 1045
• Main Authors: Christenbury, Joseph G., BS, Folgar, Francisco A., MD, O'Connell, Rachelle V., BSE, Chiu, Stephanie J., BSE, Farsiu, Sina, PhD, Toth, Cynthia A., MD
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.05.2013
• Subjects: Aged; Cell Proliferation; Cohort Studies; Disease Progression; Humans; Logistic Models; Macula Lutea - pathology; Macular Degeneration - pathology; Ophthalmology; Prospective Studies; Retinal Pigment Epithelium - pathology; Tomography, Optical Coherence

Purpose Drusen and migrating retinal pigment epithelium have been associated with hyperreflective foci (HF) detected by spectral-domain optical coherence tomography (SD-OCT). This study sought to quantify the change in intraretinal HF distribution and its correlation with age-related macular degener...