Sleep Disturbances in Patients with Schizophrenia Impact and Effect of Antipsychotics

• Published in: CNS drugs Vol. 22; no. 11; pp. 939 - 962
• Main Author: Cohrs, Stefan
• Format: Journal Article
• Language: English
• Published: Cham Springer International Publishing 01.01.2008; Adis International; Wolters Kluwer Health, Inc; Springer Nature B.V
• Subjects: Adult and adolescent clinical studies; Antipsychotic Agents - adverse effects; Antipsychotic Agents - therapeutic use; Antipsychotic drugs; Antipsychotics; Biological and medical sciences; Clozapine; Complications and side effects; Disorders of higher nervous function. Focal brain diseases. Central vestibular syndrome and deafness. Brain stem syndromes; Health aspects; Humans; Medical sciences; Medicine; Medicine & Public Health; Nervous system (semeiology, syndromes); Neurology; Neuropharmacology; Neurosciences; Olanzapine; Pharmacology. Drug treatments; Pharmacotherapy; Psychiatry; Psycholeptics: tranquillizer, neuroleptic; Psychology. Psychoanalysis. Psychiatry; Psychopathology. Psychiatry; Psychopharmacology; Psychoses; Review Article; Risk factors; Schizophrenia; Schizophrenia - complications; Schizophrenia - drug therapy; Schizophrenia - physiopathology; Sleep - drug effects; Sleep disorders; Sleep Wake Disorders - diagnosis; Sleep Wake Disorders - etiology; Sleep Wake Disorders - physiopathology; Olanzapine; Obstructive Sleep Apnoea; Clozapine; Ziprasidone; Schizophrenic Patient; Human; Nervous system diseases; Neuroleptic; Psychotropic; Toxicity; Pharmacotherapy; Schizophrenia; Sleep disorder; Review; Rapid eye movement sleep; Psychosis; Treatment; Antipsychotic; Sleep wake cycle; Neurological disorder; Bibliographic review

Difficulties initiating or maintaining sleep are frequently encountered in patients with schizophrenia. Disturbed sleep can be found in 30–80% of schizophrenic patients, depending on the degree of psychotic symptomatology. Measured by polysomnography, reduced sleep efficiency and total sleep time, a...