Acute activation of adipocyte lipolysis reveals dynamic lipid remodeling of the hepatic lipidome

• Published in: Journal of lipid research Vol. 65; no. 2; p. 100434
• Main Authors: Zhang, Sicheng, Williams, Kevin J., Verlande-Ferrero, Amandine, Chan, Alvin P., Su, Gino B., Kershaw, Erin E., Cox, James E., Maschek, John Alan, Shapira, Suzanne N., Christofk, Heather R., de Aguiar Vallim, Thomas Q., Masri, Selma, Villanueva, Claudio J.
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.02.2024; American Society for Biochemistry and Molecular Biology; Elsevier
• Subjects: Adipocytes; Adipose tissue triglyceride lipase; Ceramides; Fasting; Lipase; Lipid droplets; Lipidomics; Lipids; Liver; Triglycerides; EE; CE; NAFLD; Fasting; Lipid droplets; Liver; ATGL; Lipids; Lipidomics; Triglycerides; Adipocytes; DAG; WAT; Lipase; iWAT; AR; CER; BAT; VLCFA; Ceramides; Adipose tissue triglyceride lipase; TAG; RER

Adipose tissue is the site of long-term energy storage. During the fasting state, exercise, and cold exposure, the white adipose tissue mobilizes energy for peripheral tissues through lipolysis. The mobilization of lipids from white adipose tissue to the liver can lead to excess triglyceride accumul...