Wound microenvironment self-adaptive hydrogel with efficient angiogenesis for promoting diabetic wound healing

• Published in: Bioactive materials Vol. 20; pp. 561 - 573
• Main Authors: Shao, Zijian, Yin, Tianyu, Jiang, Jinbo, He, Yang, Xiang, Tao, Zhou, Shaobing
• Format: Journal Article
• Language: English
• Published: Elsevier B.V 01.02.2023; KeAi Publishing; KeAi Communications Co., Ltd
• Subjects: Angiogenesis; Diabetic wound healing; MMP-9 responsive; Self-adaptive hydrogel; Wound microenvironment; Angiogenesis; Self-adaptive hydrogel; Wound microenvironment; MMP-9 responsive; Diabetic wound healing

Neovascularization is critical to improve the diabetic microenvironment, deliver abundant nutrients to the wound and promote wound closure. However, the excess of oxidative stress impedes the healing process. Herein, a self-adaptive multifunctional hydrogel with self-healing property and injectabili...