Effects of bright light exposure on human fear conditioning, extinction, and associated prefrontal activation

• Published in: Physiology & behavior Vol. 194; pp. 268 - 276
• Main Authors: Yoshiike, Takuya, Honma, Motoyasu, Yamada, Naoto, Kim, Yoshiharu, Kuriyama, Kenichi
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.10.2018
• Subjects: Bright light exposure; Cerebrovascular Circulation - physiology; Conditioning (Psychology) - physiology; Cued fear conditioning; Extinction, Psychological - physiology; Fear - physiology; Fear extinction learning; Fear-circuitry disorders; fearfulness; Female; Galvanic Skin Response - physiology; hemodynamics; Humans; Male; memory; Mental Recall - physiology; Near-infrared spectroscopy; Photic Stimulation; Phototherapy - methods; Prefrontal cortex; Prefrontal Cortex - diagnostic imaging; Prefrontal Cortex - physiology; Single-Blind Method; Spectroscopy, Near-Infrared; therapeutics; Time Factors; Visual Perception - physiology; Young Adult; Cued fear conditioning; Bright light exposure; Fear extinction learning; Fear-circuitry disorders; Prefrontal cortex; Near-infrared spectroscopy

Bright light (BL) not only regulates human emotion and circadian physiology but can also directly modulate emotional memories. Impaired fear extinction and enhanced fear acquisition and consolidation are hallmarks of fear-circuitry disorders; thus, we tested whether BL facilitates fear extinction an...