NK cells from Men Who Have Sex with Men at high risk for HIV-1 infection exhibit higher effector capacity

• Published in: Scientific reports Vol. 13; no. 1; pp. 16766 - 13
• Main Authors: Rincón, Daniel S., Flórez-Álvarez, Lizdany, Taborda, Natalia A., Hernandez, Juan C., Rugeles, María T., Zapata-Builes, Wildeman
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 05.10.2023; Nature Publishing Group; Nature Portfolio
• Subjects: 631/250/255; 692/699; 692/699/255; Antiviral drugs; CD4 antigen; CD69 antigen; Effector cells; Granzyme B; Health risks; HIV; Human immunodeficiency virus; Humanities and Social Sciences; Infections; Lymphocytes T; multidisciplinary; NKG2 antigen; p24 Protein; RANTES; Risk taking; Science; Science (multidisciplinary); Sexual behavior; Sexually transmitted diseases; STD; γ-Interferon

Despite being under constant exposure to HIV-1, some individuals do not show serological or clinical evidence of infection and are known as HESN (HIV-Exposed Seronegative). Multiple studies in different HESN cohorts have linked the NK cells as a correlate of resistance; however, little is known abou...