cblaster: a remote search tool for rapid identification and visualization of homologous gene clusters

• Published in: Bioinformatics advances Vol. 1; no. 1; p. vbab016
• Main Authors: Gilchrist, Cameron L M, Booth, Thomas J, van Wersch, Bram, van Grieken, Liana, Medema, Marnix H, Chooi, Yit-Heng
• Format: Journal Article
• Language: English
• Published: England Oxford University Press 2021
• Subjects: Bioinformatics; Computer graphics; Drug metabolism; Drug resistance; Gene clusters; Genes; Genomics; Original Paper; Virulence

Motivation Genes involved in coordinated biological pathways, including metabolism, drug resistance and virulence, are often collocalized as gene clusters. Identifying homologous gene clusters aids in the study of their function and evolution, however, existing tools are limited to searching local s...