Effect of intermittent and continuous caloric restriction on Sirtuin1 concentration depends on sex and body mass index

• Published in: Nutrition, metabolism, and cardiovascular diseases Vol. 31; no. 6; pp. 1871 - 1878
• Main Authors: Opstad, Trine B., Sundfør, Tine, Tonstad, Serena, Seljeflot, Ingebjørg
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 07.06.2021
• Subjects: blood; BMI; body mass index; body weight; Caloric restriction; correlation; energy; homeostasis; low calorie diet; metabolism; nutrient availability; nutritional intervention; population; Sex; Sirtuin1; sirtuins; CVD; NAD; CCR; IL; Sex; STACs; ICR; SIRT1; Sirtuin1; Caloric restriction; BMI; CR

The favorable effect of caloric restriction (CR) on health span is well known and partly mediated by the sirtuin system. Sirtuin1, a regulator of energy homeostasis in response to nutrient availability, is activated by CR. We therefore investigated effects of two different CR regimens on Sirtuin1 co...