Atypical structure and phylogenomic evolution of the new eutherian oocyte- and embryo-expressed KHDC1/DPPA5/ECAT1/OOEP gene family

• Published in: Genomics (San Diego, Calif.) Vol. 90; no. 5; pp. 583 - 594
• Main Authors: Pierre, Alice, Gautier, Mathieu, Callebaut, Isabelle, Bontoux, Martine, Jeanpierre, Eric, Pontarotti, Pierre, Monget, Philippe
• Format: Journal Article
• Language: English
• Published: San Diego, CA Elsevier Inc 01.11.2007; Elsevier
• Subjects: Amino Acid Sequence; Animals; Atypical phylogenetic evolution; Biological and medical sciences; Computational Biology; Computer Science; DNA-Binding Proteins - genetics; DNA-Binding Proteins - metabolism; Dppa5; ECATI; Embryonic Stem Cells - metabolism; Eutherian mammals; Evolution, Molecular; Female; Fundamental and applied biological sciences. Psychology; Genes. Genome; Genetics of eukaryotes. Biological and molecular evolution; Genome; Homeodomain Proteins - genetics; Homeodomain Proteins - metabolism; In Situ Hybridization; Life Sciences; Mice; Molecular and cellular biology; Molecular genetics; Molecular Sequence Data; Multigene Family; Nanog Homeobox Protein; Oocyte; Oocytes - metabolism; Phylogeny; Proteins - genetics; Proteins - metabolism; Reverse Transcriptase Polymerase Chain Reaction; Sequence Homology, Amino Acid; Atypical phylogenetic evolution; Dppa5; ECATI; Eutherian mammals; Oocyte; Embryo; Genomics; Germinal cell; Gene expression; Molecular evolution; Vertebrata; Mammalia; Multigene family; EUTHERIEN

Several recent studies have shown that genes specifically expressed by the oocyte are subject to rapid evolution, in particular via gene duplication mechanisms. In the present work, we have focused our attention on a family of genes, specific to eutherian mammals, that are located in unstable genomi...