Pharmacological interventions and hormonal therapies for depressive symptoms in peri- and post-menopausal women: a network meta-analysis of randomized controlled trials

• Published in: Psychiatry Research Vol. 326; p. 115316
• Main Authors: Tseng, Ping-Tao, Chiu, Hsien-Jane, Suen, Mein-Woei, Zeng, Bing-Syuan, Wu, Ming-Kung, Tu, Yu-Kang, Hung, Kuo-Chuan, Wu, Yi-Cheng, Su, Kuan-Pin, Li, Dian-Jeng, Chen, Tien-Yu, Stubbs, Brendon, Carvalho, Andre F, Solmi, Marco, Thompson, Trevor, Caruso, Maria Gabriella, Matsuoka, Yutaka J., Chen, Yen-Wen, Lin, Pao-Yen, Sun, Cheuk-Kwan, Cheng, Yu-Shian, Shiue, Yow-Ling
• Format: Journal Article
• Language: English
• Published: Ireland Elsevier B.V 01.08.2023; Elsevier BV
• Subjects: Depression; Depression - drug therapy; Efficacy; Female; Fluoxetine; Fluoxetine - therapeutic use; Humans; Menopause; Middle Aged; Network Meta-Analysis; Postmenopause; Randomized Controlled Trials as Topic; Systematic review; Tolerability; Efficacy; Systematic review; Depression; Tolerability; Menopause

•Hormone replacement therapy +/- antidepressants can relieve menopausal depression.•Fluoxetine + oral combined estrogen-progesterone therapy best reduce depression.•Similar finding was also noted in subjects with definite depression diagnosis. Although significant portion of women experience depress...