Serum fetuin‐A and Ser312 phosphorylated fetuin‐A responses and markers of insulin sensitivity after a single bout of moderate intensity exercise

• Published in: Physiological reports Vol. 9; no. 5; pp. e14773 - n/a
• Main Authors: Ren, Guang, Bowers, Robert L., Kim, Teayoun, Mahurin, Alonzo J., Grandjean, Peter W., Mathews, Suresh T.
• Format: Journal Article
• Language: English
• Published: United States John Wiley & Sons, Inc 01.03.2021; John Wiley and Sons Inc; Wiley
• Subjects: Adipose tissue; Adipose Tissue - metabolism; alpha-2-HS-Glycoprotein - metabolism; Body weight; Body weight loss; Diabetes; Diabetes mellitus (non-insulin dependent); Diabetes Mellitus, Type 2; Exercise; Exercise - physiology; Fatty liver; fetuin‐A; Fitness training programs; Glucose; Glucose tolerance; Homeostasis; Humans; Insulin; Insulin - blood; Insulin resistance; Insulin Resistance - physiology; insulin sensitivity; Kinases; Laboratories; Liver diseases; Metabolism; Musculoskeletal system; Obesity; Obesity - blood; Original; phosphofetuin‐A; Phosphorylation; Physical fitness; Protein-tyrosine kinase receptors; Quality control; single bout exercise; Software; Walking; Weight control; Weight Loss - physiology; fetuin-A; insulin sensitivity; phosphofetuin-A; obesity; single bout exercise

Fetuin‐A (Fet‐A), secreted by the liver and adipose tissue, inhibits insulin receptor tyrosine kinase activity and modulates insulin action. Numerous studies have shown association of elevated serum Fet‐A concentrations with obesity, non‐alcoholic fatty liver disease, and type 2 diabetes. Both moder...