Effects of intraarticular ropivacaine and morphine on lipopolysaccharide‐induced synovitis in horses

• Published in: Veterinary anaesthesia and analgesia Vol. 36; no. 3; pp. 280 - 286
• Main Authors: Santos, Luiz César Pereira, De Moraes, Aury Nunes, Saito, Mere Erika
• Format: Journal Article
• Language: English
• Published: Oxford, UK Elsevier Ltd 01.05.2009; Oxford, UK : Blackwell Publishing Ltd; Blackwell Publishing Ltd
• Subjects: adult animals; Amides - administration & dosage; Amides - pharmacology; analgesia; Analgesics - administration & dosage; Analgesics - pharmacology; Animals; combination drug therapy; Cross-Over Studies; Drug Therapy, Combination; equine; Escherichia coli; Female; forelimbs; Horse Diseases - chemically induced; Horse Diseases - drug therapy; Horses; Injections, Intra-Articular - veterinary; intraarticular; intravenous injection; lipopolysaccharides; Lipopolysaccharides - toxicity; Male; morphine; Morphine - administration & dosage; Morphine - pharmacology; pain; ropivacaine; synovitis; Synovitis - chemically induced; Synovitis - drug therapy; Synovitis - veterinary; ropivacaine; intraarticular; analgesia; synovitis; equine; morphine

To compare the intraarticular (IA) analgesic effects of ropivacaine and morphine in horses with experimentally induced synovitis. Randomized, blinded cross‐over design. Twelve healthy mixed breed horses between 8–15 years old. Synovitis was induced in the left radio‐carpal joint with an injection of...