Plasmonic nanostructure-enhanced Raman scattering for detection of SARS-CoV-2 nucleocapsid protein and spike protein variants

• Published in: Analytica chimica acta Vol. 1239; p. 340651
• Main Authors: Yeh, Yi-Jui, Le, Trong-Nghia, Hsiao, Wesley Wei-Wen, Tung, Kuo-Lun, Ostrikov, Kostya (Ken), Chiang, Wei-Hung
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 25.01.2023
• Subjects: COVID-19 - diagnosis; Humans; Limit of Detection; Nanostructures - chemistry; Pathogen detection; Point-of-care test; Raman spectroscopy; Rapid diagnosis; SARS-CoV-2; SERS; Spectrum Analysis, Raman - methods; Spike Glycoprotein, Coronavirus; Rapid diagnosis; Pathogen detection; Point-of-care test; SARS-CoV-2; Raman spectroscopy; SERS

Epidemiological control and public health monitoring during the outbreaks of infectious viral diseases rely on the ability to detect viral pathogens. Here we demonstrate a rapid, sensitive, and selective nanotechnology-enhanced severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) detection b...