CD105+ fibroblasts support an immunosuppressive niche in women at high risk of breast cancer initiation - Carlson, Eric G.; Lopez, Jennifer C.; Yamaguchi, Yukiko; Gibson, Jackson; Priceman, Saul J.; LaBarge, Mark A. (Breast cancer research : BCR, 2025)
Keywords: Adipogenesis; Adolescent; Adult; Aged; Aging; Antibodies; BRCA1; BRCA1 protein; BRCA1 Protein - genetics; Breast cancer; Breast Neoplasms - etiology; Breast Neoplasms - genetics; Breast Neoplasms - immunology; Breast Neoplasms - metabolism; Breast Neoplasms - pathology; Cancer; Cancer-Associated Fibroblasts - immunology; Cancer-Associated Fibroblasts - metabolism; Cancer-Associated Fibroblasts - pathology; CD105 antigen; Cell proliferation; Coculture Techniques; Disease susceptibility; Endoglin - metabolism; Epithelial cells; Ethylenediaminetetraacetic acid; Female; Fibroblasts; Fibroblasts - immunology; Fibroblasts - metabolism; Health aspects; Human subjects; Humans; Immune system; Immunosuppressive; Immunosurveillance; Inflammation; Intralobular fibroblasts; Lymphocytes T; Macrophages; Macrophages - immunology; Macrophages - metabolism; Mammary gland; Middle Aged; Mutation; Polarization; Review boards; Risk factors; Stroma; Tumor Microenvironment - immunology; Young Adult; Aging; Immunosuppressive; Intralobular fibroblasts; BRCA1; Macrophages