Ferroptosis in liver disease: new insights into disease mechanisms

• Published in: Cell death discovery Vol. 7; no. 1; p. 276
• Main Authors: Wu, Jing, Wang, Yi, Jiang, Rongtao, Xue, Ran, Yin, Xuehong, Wu, Muchen, Meng, Qinghua
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 05.10.2021; Springer Nature B.V; Nature Publishing Group
• Subjects: 692/699/1503/1607; 692/699/1503/1607/1610/4029; Apoptosis; Biochemistry; Biomedical and Life Sciences; Cell Biology; Cell Cycle Analysis; Cell death; Cytosol; Fatty liver; Ferroptosis; GTP cyclohydrolase; Hemochromatosis; Hepatocellular carcinoma; Ischemia; Life Sciences; Lipid peroxidation; Liver diseases; Mitochondria; Molecular modelling; p53 Protein; Pathophysiology; Reperfusion; Review; Review Article; Stem Cells; Therapeutic targets

Characterized by excessive iron accumulation and lipid peroxidation, ferroptosis is a novel form of iron-dependent cell death, which is morphologically, genetically, and biochemically distinct from other well-known cell death. In recent years, ferroptosis has been quickly gaining attention in the fi...