The SARS-CoV-2 Omicron BA.1 spike G446S mutation potentiates antiviral T-cell recognition

Although the Omicron variant of the SARS-CoV-2 virus shows resistance to neutralizing antibody, it retains susceptibility to the cellular immune response. Here we characterize vaccine-induced T cells specific for various SARS-CoV-2 variants and identified HLA-A*24:02-restricted CD8 + T cells that st...

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Bibliographic Details
Published inNature communications Vol. 13; no. 1; p. 5440
Main Authors Motozono, Chihiro, Toyoda, Mako, Tan, Toong Seng, Hamana, Hiroshi, Goto, Yoshihiko, Aritsu, Yoshiki, Miyashita, Yusuke, Oshiumi, Hiroyuki, Nakamura, Kimitoshi, Okada, Seiji, Udaka, Keiko, Kitamatsu, Mizuki, Kishi, Hiroyuki, Ueno, Takamasa
Format Journal Article
LanguageEnglish
Published London Nature Publishing Group UK 21.09.2022
Nature Publishing Group
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