Computational systems biology in disease modeling and control, review and perspectives

• Published in: NPJ systems biology and applications Vol. 8; no. 1; pp. 37 - 16
• Main Authors: Yue, Rongting, Dutta, Abhishek
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 03.10.2022; Nature Publishing Group; Nature Portfolio
• Subjects: 631/114; 631/553/1833; 631/553/2702; 631/553/2711; 631/553/2712; Bioinformatics; Biomedical and Life Sciences; Computational Biology/Bioinformatics; Computer Appl. in Life Sciences; Computer applications; Disease; Life Sciences; Mathematical models; Proteomics; Review; Review Article; Systems Biology; Toxicity

Omics-based approaches have become increasingly influential in identifying disease mechanisms and drug responses. Considering that diseases and drug responses are co-expressed and regulated in the relevant omics data interactions, the traditional way of grabbing omics data from single isolated layer...