Organ biodistribution, clearance, and genotoxicity of orally administered zinc oxide nanoparticles in mice - Li, Ching-Hao; Shen, Chuan-Chou; Cheng, Yu-Wen; Huang, Shih-Hsuan; Wu, Chung-Che; Kao, Chen-Chieh; Liao, Jiunn-Wang; Kang, Jaw-Jou (Nanotoxicology, 2012)
Keywords: Absorption; Administration, Oral; Analysis of Variance; Animals; biodistribution; Cell Survival - drug effects; clearance; Cytotoxicity; Female; Human Umbilical Vein Endothelial Cells - cytology; Human Umbilical Vein Endothelial Cells - drug effects; Humans; Hydrogen-Ion Concentration; Injections, Intraperitoneal; Kidney - chemistry; Kidney - metabolism; Liver - chemistry; Liver - metabolism; Male; Mice; Mice, Inbred ICR; Micronucleus Tests; nanoparticles; Nanoparticles - administration & dosage; Nanoparticles - toxicity; Particle Size; Solubility; Spleen - chemistry; Spleen - metabolism; Superoxides - metabolism; Tissue Distribution; Toxicity Tests, Acute; Zinc oxide; Zinc Oxide - administration & dosage; Zinc Oxide - pharmacokinetics; Zinc Oxide - toxicity