Molecular remission at T cell level in patients with rheumatoid arthritis

• Published in: Scientific reports Vol. 11; no. 1; pp. 16691 - 9
• Main Authors: Inamo, Jun, Suzuki, Katsuya, Takeshita, Masaru, Kondo, Yasushi, Okuzono, Yuumi, Koga, Keiko, Kassai, Yoshiaki, Takiguchi, Maiko, Kurisu, Rina, Yoshimura, Akihiko, Takeuchi, Tsutomu
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 17.08.2021; Nature Publishing Group; Nature Portfolio
• Subjects: 631/114/1305; 631/114/2413; 631/337/2019; 692/4023/1670/498; Autoimmune diseases; CD4 antigen; CD8 antigen; Disease control; Gene expression; Humanities and Social Sciences; Learning algorithms; Lymphocytes; Lymphocytes T; Molecular modelling; Monoclonal antibodies; multidisciplinary; Patients; Principal components analysis; Remission; Remission (Medicine); Rheumatoid arthritis; Science; Science (multidisciplinary)

While numerous disease-modifying anti-rheumatic drugs (DMARDs) have brought about a dramatic paradigm shift in the management of rheumatoid arthritis (RA), unmet needs remain, such as the small proportion of patients who achieve drug-free status. The aim of this study was to explore key molecules fo...