Biosurfactant-Mediated Membrane Depolarization Maintains Viability during Oxygen Depletion in Bacillus subtilis

• Published in: Current biology Vol. 30; no. 6; pp. 1011 - 1022.e6
• Main Authors: Arjes, Heidi A., Vo, Lam, Dunn, Caroline M., Willis, Lisa, DeRosa, Christopher A., Fraser, Cassandra L., Kearns, Daniel B., Huang, Kerwyn Casey
• Format: Journal Article
• Language: English
• Published: England Elsevier Inc 23.03.2020
• Subjects: aerobic respiration; Bacillus subtilis - physiology; Bacterial Proteins - metabolism; biosurfactant; cell lysis; Cell Membrane - physiology; hypoxia; membrane depolarization; membrane potential; Oxygen - metabolism; oxygen depletion; oxygen diffusion; surfactin; surfactin; oxygen diffusion; hypoxia; biosurfactant; oxygen depletion; membrane depolarization; membrane potential; aerobic respiration; cell lysis

The presence or absence of oxygen in the environment is a strong effector of cellular metabolism and physiology. Like many eukaryotes and some bacteria, Bacillus subtilis primarily utilizes oxygen during respiration to generate ATP. Despite the importance of oxygen for B. subtilis survival, we know...