The role of pancreas to improve hyperglycemia in STZ-induced diabetic rats by thiamine disulfide

• Published in: Nutrition & diabetes Vol. 12; no. 1; p. 32
• Main Authors: Rad, Mahtab Ghanbari, Sharifi, Mohammadreza, Meamar, Rokhsareh, Soltani, Nepton
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 20.06.2022; Nature Publishing Group
• Subjects: 38/39; 631/443/319; 692/163/2743/137/1418; 96/95; Clinical Nutrition; Diabetes; Epidemiology; Glucagon; Glucose; Hyperglycemia; Insulin; Internal Medicine; Medicine; Medicine & Public Health; Metabolic Diseases; Pancreas; Rodents; Vitamin B

Background The present study investigated the effect of thiamine disulfide (TD) on the pancreas in terms of hyperglycemia improvement and insulin sensitivity increase in diabetic male rats. We also aimed to study the function of Pdx1 (pancreatic and duodenal homeobox 1) and Glut2 (glucose transporte...