Advances in high-speed atomic force microscopy (HS-AFM) reveal dynamics of transmembrane channels and transporters

• Published in: Current opinion in structural biology Vol. 57; pp. 93 - 102
• Main Authors: Heath, George R, Scheuring, Simon
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 01.08.2019

•HS-AFM detects conformational changes of unlabeled membrane proteins.•In situ responses to pH, ligands, temperature and light can be visualized.•Developments in techniques now allow microsecond temporal resolution. Recent advances in high-speed atomic force microscopy (HS-AFM) have made it possible...