Development and validation of a gas chromatography method for the determination of β-caryophyllene in clove extract and its application

• Published in: Scientific reports Vol. 11; no. 1; p. 13853
• Main Authors: Park, Mi Hee, Kim, Chul Jin, Lee, Jin Young, Kim, In Seon, Kim, Sung-Kyu
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 05.07.2021; Nature Publishing Group; Nature Portfolio
• Subjects: 631/1647; 639/301; 692/700; 704/445; Accuracy; Apoptosis; Calibration; Cancer; Caryophyllene; Cell cycle; Chromatography; Clinical trials; Correlation coefficient; Flowers & plants; Gas chromatography; Humanities and Social Sciences; multidisciplinary; Plant extracts; Proteins; Quality control; Reproducibility; Science; Science (multidisciplinary); Standard deviation

The purpose of this study is to check the effectiveness of the analysis method that separates and quantifies β-caryophyllene among clove extracts and validate according to current ICH guidelines. The β-caryophyllene was active constituent of clove buds. The developed method gave a good detection res...