pH-Responsive mesoporous silica nanoparticle-reinforced composite resin with remineralization capability

• Published in: BMC oral health Vol. 25; no. 1; pp. 1234 - 16
• Main Authors: Ge, Yongcheng, Zhao, Ting, Liu, Yuguang, Fan, Sizheng, Liu, Pengyuan, Zhao, Chengji, Liu, Xiaoqiu
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 23.07.2025; BioMed Central; BMC
• Subjects: Acids; Biocompatibility; Calcium ion release; Calcium phosphate; Calcium phosphates; Calcium Phosphates - chemistry; Caustic soda; Cell Survival - drug effects; Cell viability; Chitosan; Chitosan - chemistry; Cholecystokinin; Composite materials; Composite Resins - chemistry; Cytotoxicity; Dental caries; Dental cement; Dental composite; Dental restorative materials; Dentin; Elastic Modulus; Ethanol; Ethylenediaminetetraacetic acid; Flexural Strength; Hardness; Humans; Hydrogen-Ion Concentration; Interfacial bonding; Materials Testing; Mechanical properties; Mesoporous silica nanoparticle; Mineralization; Nanoparticles; Nanoparticles - chemistry; NMR; Nuclear magnetic resonance; pH effects; Polymerization; Porosity; Remineralization; Resins; Silica; Silicon Dioxide - chemistry; Tooth Remineralization - methods; Vacuum distillation; China; California; United States > US; Shanghai China; Dentin; Mesoporous silica nanoparticle; Calcium ion release; Dental composite; Remineralization

Enhancing the mechanical properties of composite resins and promoting dentin remineralization are effective strategies for extending the longevity of restorations. In this study, we developed a pH-responsive composite resin reinforced with phosphorylated chitosan (Pchi)/amorphous calcium phosphate (...