Detection of Mycobacterium tuberculosis DNA in CD34+ peripheral blood mononuclear cells of adults with tuberculosis infection and disease

• Published in: International journal of infectious diseases Vol. 141; p. 106999
• Main Authors: Repele, Federica, Alonzi, Tonino, Navarra, Assunta, Farroni, Chiara, Salmi, Andrea, Cuzzi, Gilda, Delogu, Giovanni, Gualano, Gina, Puro, Vincenzo, De Carli, Gabriella, Girardi, Enrico, Palmieri, Fabrizio, Martineau, Adrian R., Goletti, Delia
• Format: Journal Article
• Language: English
• Published: Canada Elsevier Ltd 01.04.2024; Elsevier
• Subjects: CD34+ cells; ddPCR; IGRA; Mycobacterium tuberculosis; Tuberculosis infection; Tuberculosis niche; ddPCR; Tuberculosis infection; Tuberculosis niche; Mycobacterium tuberculosis; IGRA; CD34+ cells; CD34(+) cells

•Mycobacterium tuberculosis (Mtb) DNA is detected in the peripheral blood cells of donors with tuberculosis (TB) or TB infection.•Mtb DNA is detected in the peripheral blood cells of donors with presumptive TB.•Mtb DNA detection is more frequent in peripheral CD34+ cells.•CD34+ cells may represent a...