Pathological fear, anxiety and negative affect exhibit distinct neurostructural signatures: evidence from psychiatric neuroimaging meta-analysis

• Published in: Translational psychiatry Vol. 12; no. 1; pp. 405 - 19
• Main Authors: Liu, Xiqin, Klugah-Brown, Benjamin, Zhang, Ran, Chen, Huafu, Zhang, Jie, Becker, Benjamin
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 23.09.2022; Nature Publishing Group
• Subjects: 59/57; 631/477/2811; 692/699/476; Behavioral Sciences; Biological Psychology; Brain research; Fear & phobias; Generalized anxiety disorder; Laboratories; Medical imaging; Medicine; Medicine & Public Health; Mental depression; Mental disorders; Meta-analysis; Neurobiology; Neuroimaging; Neurosciences; Panic attacks; Patients; Pharmacotherapy; Psychiatry; Social anxiety

Internalizing disorders encompass anxiety, fear and depressive disorders, which exhibit overlap at both conceptual and symptom levels. Given that a neurobiological evaluation is lacking, we conducted a Seed-based D-Mapping comparative meta-analysis including coordinates as well as original statistic...