lncRNA FER1L4 is dysregulated in osteoarthritis and regulates IL-6 expression in human chondrocyte cells

• Published in: Scientific reports Vol. 11; no. 1; pp. 13032 - 9
• Main Authors: He, Jinhai, Wang, Li, Ding, Yajun, Liu, Hongbing, Zou, Guoyou
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 22.06.2021; Nature Publishing Group; Nature Portfolio
• Subjects: 631/208/721; 692/53/2421; Aging; Arthritis; Chondrocytes; Correlation analysis; Humanities and Social Sciences; Interleukin 6; Joint diseases; multidisciplinary; Osteoarthritis; Physical activity; Plasma; Science; Science (multidisciplinary); Synovial fluid

Osteoarthritis (OA) is the most prevalent joint disease and is one of the major causes of disability in the world. There has been an increase in the incidence of OA, which is associated with an aging population, sedentary lifestyle, and reduced physical activity. Due to the complex OA pathogenesis,...