Neural Correlates of Decision Thresholds in the Human Subthalamic Nucleus

• Published in: Current biology Vol. 26; no. 7; pp. 916 - 920
• Main Authors: Herz, Damian M., Zavala, Baltazar A., Bogacz, Rafal, Brown, Peter
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 04.04.2016; Cell Press
• Subjects: Decision Making; Deep Brain Stimulation; Electroencephalography; Humans; Impulsive Behavior; Neuropsychological Tests; Parkinson Disease - physiopathology; Parkinson Disease - therapy; Prefrontal Cortex - physiology; Subthalamic Nucleus - physiology

If humans are faced with difficult choices when making decisions, the ability to slow down responses becomes critical in order to avoid suboptimal choices. Current models of decision making assume that the subthalamic nucleus (STN) mediates this function by elevating decision thresholds, thereby req...