Decreased GLUT2 and glucose uptake contribute to insulin secretion defects in MODY3/HNF1A hiPSC-derived mutant β cells - Low, Blaise Su Jun; Lim, Chang Siang; Ding, Shirley Suet Lee; Tan, Yaw Sing; Ng, Natasha Hui Jin; Krishnan, Vidhya Gomathi; Ang, Su Fen; Neo, Claire Wen Ying; Verma, Chandra S.; Hoon, Shawn; Lim, Su Chi; Tai, E. Shyong; et al. (Nature communications, 2021)
Keywords: 13/100; 38/91; 631/532/1360; 631/532/2064/2158; 692/163/2743; 692/699/2743/137; Beta cells; Binding; Defects; Deoxyribonucleic acid; Diabetes; Diabetes mellitus; DNA; Gene expression; Genomes; Glucose; Glucose transporter; HNF1a gene; Humanities and Social Sciences; Insulin; Insulin secretion; Molecular dynamics; multidisciplinary; Mutation; Pancreas; Pluripotency; Science; Science (multidisciplinary); Secretion; Stem cells; Transcription