Neuroanatomical Diversity of Corpus Callosum and Brain Volume in Autism: Meta-analysis, Analysis of the Autism Brain Imaging Data Exchange Project, and Simulation

• Published in: Biological psychiatry (1969) Vol. 78; no. 2; pp. 126 - 134
• Main Authors: Lefebvre, Aline, Beggiato, Anita, Bourgeron, Thomas, Toro, Roberto
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 15.07.2015; Elsevier
• Subjects: Adolescent; Adult; Autism; Autistic Disorder; Autistic Disorder - pathology; Autistic Disorder - psychology; Brain; Brain - pathology; Brain volume; Child; Child, Preschool; Cognitive science; Computational neuroanatomy; Corpus Callosum; Corpus Callosum - pathology; Databases, Factual; Female; Human health and pathology; Humans; Intelligence; Life Sciences; Male; Meta-analysis; Psychiatric/Mental Health; Psychiatrics and mental health; Statistical power; Young Adult; Autism; Brain volume; Computational neuroanatomy; Statistical power; Corpus callosum; Meta-analysis

Patients with autism have been often reported to have a smaller corpus callosum (CC) than control subjects. We conducted a meta-analysis of the literature, analyzed the CC in 694 subjects of the Autism Brain Imaging Data Exchange project, and performed computer simulations to study the effect of dif...