Bioactive Lipids in COVID-19-Further Evidence

• Published in: Archives of medical research Vol. 52; no. 1; pp. 107 - 120
• Main Author: Das, Undurti N.
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.01.2021; IMSS. Published by Elsevier Inc
• Subjects: Animals; Arachidonic acid; Arachidonic Acid - administration & dosage; Arachidonic Acid - blood; Bioactive lipids; COVID-19; COVID-19 - blood; COVID-19 - immunology; COVID-19 Drug Treatment; Cytokines; Cytokines - immunology; Humans; Inflammation; Lipids - administration & dosage; Lipids - blood; Opinion; Rats; SARS-CoV-2; SARS-CoV-2 - isolation & purification; COVID-19; SARS-CoV-2; Inflammation; Bioactive lipids; Cytokines; Arachidonic acid

Previously, I suggested that arachidonic acid (AA, 20:4 n-6) and similar bioactive lipids (BALs) inactivate SARS-CoV-2 and thus, may be of benefit in the prevention and treatment of COVID-19. This proposal is supported by the observation that (i) macrophages and T cells (including NK cells, cytotoxi...