Long-term experience in autologous in vitro endothelialization of infrainguinal ePTFE grafts

• Published in: Journal of vascular surgery Vol. 49; no. 2; pp. 352 - 362
• Main Authors: Deutsch, Manfred, MD, Meinhart, Johann, PhD, Zilla, Peter, MD, PhD, Howanietz, Norbert, MD, Gorlitzer, Michael, MD, Froeschl, Alexander, MD, Stuempflen, Andreas, MD, Bezuidenhout, Deon, PhD, Grabenwoeger, Martin, MD
• Format: Journal Article
• Language: English
• Published: United States Mosby, Inc 01.02.2009
• Subjects: Aged; Blood Vessel Prosthesis; Blood Vessel Prosthesis Implantation - adverse effects; Blood Vessel Prosthesis Implantation - instrumentation; Cell Culture Techniques; Cell Proliferation; Endothelial Cells - transplantation; Feasibility Studies; Female; Fibrin Tissue Adhesive - therapeutic use; Graft Occlusion, Vascular - etiology; Humans; Limb Salvage; Lower Extremity - blood supply; Male; Middle Aged; Peripheral Arterial Disease - pathology; Peripheral Arterial Disease - physiopathology; Peripheral Arterial Disease - surgery; Polytetrafluoroethylene; Prospective Studies; Prosthesis Design; Risk Assessment; Surgery; Time Factors; Tissue Adhesives - therapeutic use; Tissue Scaffolds; Transplantation, Autologous; Treatment Outcome; Ultrasonography, Doppler, Duplex; Vascular Patency

Objective Based on a previous randomized study showing significantly superior patency rates for in vitro endothelialized expanded polytetrafluoroethylene (ePTFE) grafts we investigated whether it was feasible for a nontertiary institution to offer autologous in vitro endothelialization to all electi...