Lipidomic analysis of plant-derived extracellular vesicles for guidance of potential anti-cancer therapy

• Published in: Bioactive materials Vol. 46; pp. 82 - 96
• Main Authors: Wang, Fei, Li, Lanya, Deng, Junyao, Ai, Jiacong, Mo, Shushan, Ding, Dandan, Xiao, Yingxian, Hu, Shiqi, Zhu, Dashuai, Li, Qishan, Zeng, Yan, Chen, Zhitong, Cheng, Ke, Li, Zhenhua
• Format: Journal Article
• Language: English
• Published: China Elsevier B.V 01.04.2025; KeAi Publishing Communications Ltd; KeAi Publishing; KeAi Communications Co., Ltd
• Subjects: anti-cancer therapy; Apoptosis; Biomedical materials; Cancer therapies; Cell cycle; Cytotoxicity; Drug delivery; Drug delivery systems; Extracellular vesicles; Ginger; In vivo methods and tests; Lipidomic analysis; Lipids; Nanotechnology; p53 Protein; Plant-derived extracellular vesicles; Plants; Protein markers; Proteins; Proteomics; Sterols; Therapeutic applications; Transcriptomics; Tumors; Vesicles; Plant-derived extracellular vesicles; anti-cancer therapy; Ginger; Lipidomic analysis; Protein markers

Plant-derived extracellular vesicles (PEVs) have been regarded as a superior source for nanomedicine and drug delivery systems. Nevertheless, their clinical translation is hindered by the lack of clarity and even contradiction in their biomedical applications. Herein, we conducted a comprehensive co...