DNA Damage, n-3 Long-Chain PUFA Levels and Proteomic Profile in Brazilian Children and Adolescents

• Published in: Nutrients Vol. 13; no. 8; p. 2483
• Main Authors: Barros, Tamiris Trevisan de, Venancio, Vinicius de Paula, Hernandes, Lívia Cristina, Antunes, Lusania Maria Greggi, Hillesheim, Elaine, Salomão, Roberta Garcia, Mathias, Mariana Giaretta, Coelho-Landell, Carolina Almeida, Toffano, Roseli Borges Donegá, Almada, Maria Olimpia Ribeiro do Vale, Camelo-Junior, José Simon, Moco, Sofia, Cominetti, Ornella, Ued, Fábio da Veiga, Kaput, Jim, Monteiro, Jacqueline Pontes
• Format: Journal Article
• Language: English
• Published: Basel MDPI AG 21.07.2021; MDPI
• Subjects: Adolescents; Blood levels; Body mass index; Cell cycle; child; Children; Comet assay; Cyclin-dependent kinases; Damage detection; Deoxyribonucleic acid; DNA; DNA damage; Docosahexaenoic acid; Eicosapentaenoic acid; Ethylenediaminetetraacetic acid; Fatty acids; Gene expression; Inflammation; Nutrition; Omega-3 fatty acids; Physiology; Proteins; proteomic; Proteomics; Teenagers; Toxicity; Unsaturated fatty acids; Urban areas; Brazil; United States > US

Fatty acids play a significant role in maintaining cellular and DNA protection and we previously found an inverse relationship between blood levels of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) and DNA damage. The aim of this study was to explore differences in proteomic profiles, fo...