Synergic effect of curcumin and its structural analogue (Monoacetylcurcumin) on anti-influenza virus infection

• Published in: Yàowu shi͡p︡in fenxi Vol. 26; no. 3; pp. 1015 - 1023
• Main Authors: Richart, Sarah M., Li, Yi-Lin, Mizushina, Yoshiyuki, Chang, Yuan-Yen, Chung, Tse-Yu, Chen, Guan-Heng, Tzen, Jason Tze-Cheng, Shia, Kak-Shan, Hsu, Wei-Li
• Format: Journal Article
• Language: English
• Published: China (Republic : 1949- ) Elsevier B.V 01.07.2018; Food and Drug Administration; Taiwan Food and Drug Administration
• Subjects: AKT protein; Antibiotics; Antiviral; Antiviral activity; antiviral properties; Apoptosis; Avian flu; Curcumin; Cytotoxicity; Deoxyribonucleic acid; DNA; DNA polymerase; Drugs; food colorants; Food dyes; Haemagglutinin; Infections; Influenza; Influenza virus; Kinases; Original; Orthomyxoviridae; Phosphorylation; Studies; Synergic; synergism; turmeric; Viruses; China; Taiwan; Synergic; Antiviral; Curcumin; Haemagglutinin; Influenza virus

Curcumin (Cur), a polyphenolic compound extracted from spice and common food colourant turmeric, contains versatile bio-activities. Monoacetylcurcumin (MAC), a structural analogue of Cur, differs from Cur by acetyl modification, but retains enone groups. Comparative analysis revealed MAC effectively...