Increased salivary aldehyde dehydrogenase 1 in non-reticular oral lichen planus

• Published in: Anais brasileiros de dermatología Vol. 92; no. 2; pp. 168 - 171
• Main Authors: Mansourian, Arash, Shanbehzadeh, Najmeh, Kia, Seyed Javad, Moosavi, Mahdieh-Sadat
• Format: Journal Article
• Language: English
• Published: Spain Sociedade Brasileira de Dermatologia 01.03.2017
• Subjects: Adult; Aldehyde dehydrogenase; Aldehyde Dehydrogenase 1 Family; Biomarkers - analysis; Case-Control Studies; Cell Transformation, Neoplastic; Cross-Sectional Studies; DERMATOLOGY; Female; Humans; Investigation; Isoenzymes - analysis; Lichen planus, oral; Lichen Planus, Oral - complications; Lichen Planus, Oral - enzymology; Male; Middle Aged; Retinal Dehydrogenase - analysis; Saliva; Saliva - enzymology; Aldehyde dehydrogenase; Saliva; Lichen planus, oral

Oral lichen planus is a potentially malignant disorder. One of the malignant transformation markers is cancer stem cells. One of the proposed marker for the detection of cancer stem cells's in head and neck cancer is aldehyde dehydrogenase. Recently it is shown that aldehyde dehydrogenase 1 exp...