Hypoxia-Induced Down-regulation of BRCA1 Expression by E2Fs - Bindra, Ranjit S.; Gibson, Shannon L.; Meng, Alice; Westermark, Ulrica; Jasin, Maria; Pierce, Andrew J.; Bristow, Robert G.; Classon, Marie K.; Glazer, Peter M. (Cancer research (Chicago, Ill.), 2005)
Keywords: Biological and medical sciences; BRCA1 Protein - genetics; BRCA1 Protein - metabolism; Breast Neoplasms - genetics; Breast Neoplasms - metabolism; Cell Hypoxia; Cell physiology; Cell transformation and carcinogenesis. Action of oncogenes and antioncogenes; Chromatin Immunoprecipitation; Colonic Neoplasms - genetics; Colonic Neoplasms - metabolism; DNA Repair; Down-Regulation; E2F Transcription Factors - genetics; E2F Transcription Factors - metabolism; Fundamental and applied biological sciences. Psychology; Gene Expression Regulation, Neoplastic; Gynecology. Andrology. Obstetrics; Humans; Hypoxia-Inducible Factor 1, alpha Subunit - genetics; Hypoxia-Inducible Factor 1, alpha Subunit - metabolism; Luciferases - metabolism; Lung Neoplasms - genetics; Lung Neoplasms - metabolism; Mammary gland diseases; Medical sciences; Molecular and cellular biology; Promoter Regions, Genetic; Recombination, Genetic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger - genetics; RNA, Messenger - metabolism; Transcription, Genetic; Tumor Cells, Cultured; Tumors; Oxygen; Transcription factor E2F; Cell microenvironment; Hypoxia; Malignant tumor; Gene expression; BRCA1 gene; Tumor suppressor gene