Calculation of the Response of Field-Effect Transistors to Charged Biological Molecules

• Published in: IEEE sensors journal Vol. 7; no. 9; pp. 1233 - 1242
• Main Authors: Landheer, D., McKinnon, W.R., Aers, G., Weihong Jiang, Deen, M.J., Shinwari, M.W.
• Format: Journal Article
• Language: English
• Published: New York IEEE 01.09.2007; The Institute of Electrical and Electronics Engineers, Inc. (IEEE)
• Subjects: Algorithms; Approximation; Biological system modeling; biomedical transducers; Biomembranes; Biosensors; Charge; Electrolytes; FETs; field-effect transistors (FETs); Insulation; Macromolecules; Mathematical analysis; Mathematical models; Membranes; modeling; Molecular biophysics; Optical signal processing; Poisson equations; Protons; Semiconductor materials; Semiconductors; Studies

Robust approximations are presented that allow for the simple calculation of the total charge and potential drop psi 0 across the region of electrolyte containing charged biological macromolecules that are attached to the gate area of a field-effect transistor (FET). The attached macromolecules are...