Magnetic Resonance Imaging More Accurately Classifies Steatosis and Fibrosis in Patients With Nonalcoholic Fatty Liver Disease Than Transient Elastography

• Published in: Gastroenterology (New York, N.Y. 1943) Vol. 150; no. 3; pp. 626 - 637.e7
• Main Authors: Imajo, Kento, Kessoku, Takaomi, Honda, Yasushi, Tomeno, Wataru, Ogawa, Yuji, Mawatari, Hironori, Fujita, Koji, Yoneda, Masato, Taguri, Masataka, Hyogo, Hideyuki, Sumida, Yoshio, Ono, Masafumi, Eguchi, Yuichiro, Inoue, Tomio, Yamanaka, Takeharu, Wada, Koichiro, Saito, Satoru, Nakajima, Atsushi
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.03.2016
• Subjects: Adult; Aged; Alanine Transaminase; Area Under Curve; Biopsy; Classification; Cross-Sectional Studies; Diagnosis; Elasticity Imaging Techniques - methods; Female; Gastroenterology and Hepatology; Humans; Liver - pathology; Liver Cirrhosis - etiology; Liver Cirrhosis - pathology; Magnetic Resonance Imaging - methods; Male; Middle Aged; Multivariate Analysis; Non-alcoholic Fatty Liver Disease - complications; Non-alcoholic Fatty Liver Disease - pathology; Overweight; Predictive Value of Tests; Prognosis; Reproducibility of Results; ROC Curve; Severity of Illness Index; MRE; NAS; NAFLD; Alanine Transaminase; MRI; CI; LSM; AUROC; NASH; ROI; Overweight; PDFF; TE; CAP; Classification; Diagnosis; NAFL; BMI; magnetic resonance imaging; transient elastography; nonalcoholic steatohepatitis; magnetic resonance elastography; area under the receiver operating characteristic; liver stiffness measurement; nonalcoholic fatty liver; body mass index; controlled attenuation parameter; proton density fat fraction; Nonalcoholic Fatty Liver Disease Activity Score; nonalcoholic fatty liver disease; region of interest; confidence interval

Noninvasive methods have been evaluated for the assessment of liver fibrosis and steatosis in patients with nonalcoholic fatty liver disease (NAFLD). We compared the ability of transient elastography (TE) with the M-probe, and magnetic resonance elastography (MRE) to assess liver fibrosis. Findings...